SCHEMBL6159022

SCHEMBL6159022

CCOC(=O)NC(=Cc1ccccc1)C(=O)OCC

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 6/20 0.64
KMT2A Q03164 6/20 0.64
ALDH1A1 P00352 3/20 0.59
POLB P06746 2/20 0.59
LMNA P02545 6/20 0.53
KDM4E B2RXH2 2/20 0.53
RAB9A P51151 4/20 0.52
SMN1; SMN2 Q16637 3/20 0.52
NPC1 O15118 2/20 0.52
MAPT P10636 5/20 0.51
NPSR1 Q6W5P4 4/20 0.51
S1PR4 O95977 1/20 0.51
S1PR1 P21453 1/20 0.51
MAPK1 P28482 1/20 0.51
NR1H4 Q96RI1 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.48
CYP1A2 P05177 1/20 0.48
CYP2C9 P11712 1/20 0.48
CYP2C19 P33261 1/20 0.48
GAA P10253 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10962508 1.00 MEN1 (0.64) MEN1KMT2AALDH1A1POLBLMNA
SCHEMBL9487630 0.88 MEN1 (0.64) MEN1KMT2AALDH1A1POLBLMNA
SCHEMBL9487628 0.88 MEN1 (0.64) MEN1KMT2AALDH1A1POLBLMNA
SCHEMBL29727512 0.84 MEN1 (0.59) MEN1KMT2AALDH1A1LMNAKDM4E
SCHEMBL3295689 0.84 ALDH1A1 (0.55) MEN1KMT2AALDH1A1POLBLMNA
SCHEMBL3494804 0.82 MEN1 (0.64) MEN1KMT2AALDH1A1POLBLMNA
SCHEMBL319887 0.82 ALDH1A1 (0.67) MEN1KMT2AALDH1A1POLBLMNA
SCHEMBL3494802 0.82 MEN1 (0.64) MEN1KMT2AALDH1A1POLBLMNA
SCHEMBL28327535 0.81 MEN1 (0.62) MEN1KMT2AALDH1A1POLBLMNA
SCHEMBL17138039 0.79 TDP1 (0.51) MEN1KMT2AALDH1A1POLBLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0856262-B1 Use of a coated polytetrafluoroethylene article in a garment GORE & ASS (US) 2005-02-09 EP disclosed
EP-0690881-B1 PROCESS FOR THE PREPARATION OF COATED ARTICLES AND THE USE THEREOF GORE & ASS (US) 1999-04-21 EP disclosed
EP-0856262-A1 Use of a coated polytetrafluoroethylene article in a garment W.L. GORE & ASSOCIATES, INC. (US) 1998-08-05 EP disclosed
US-5539047-A Microemulsion polymerization systems and coated materials made therefrom W. L. GORE & ASSOCIATES, INC. (US) 1996-07-23 US disclosed
EP-0690881-A1 MICROEMULSION POLYMERIZATION SYSTEMS AND COATED MATERIALS MADE THEREFROM W.L. GORE & ASSOCIATES, INC. (US) 1996-01-10 EP disclosed
US-5385694-A Microemulsion polymerization systems and coated materials made therefrom W. L. GORE & ASSOCIATES, INC. (US) 1995-01-31 US disclosed
US-5376441-A Microemulsion polymerization systems and coated materials made therefrom W. L. GORE & ASSOCIATES, INC. (US) 1994-12-27 US disclosed
WO-1994022928-A1 MICROEMULSION POLYMERIZATION SYSTEMS AND COATED MATERIALS MADE THEREFROM W.L. GORE & ASSOCIATES, INC. (US) 1994-10-13 WO disclosed
US-4515731-A Asymmetric catalysis MONSANTO COMPANY (US) 1985-05-07 US disclosed