SCHEMBL3295689

SCHEMBL3295689

C=CC(=O)C(=Cc1ccccc1)NC(=O)OCC

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.55
POLB P06746 1/20 0.55
MEN1 O00255 3/20 0.51
KMT2A Q03164 3/20 0.51
RAB9A P51151 6/20 0.49
NPC1 O15118 4/20 0.49
SMN1; SMN2 Q16637 3/20 0.49
LMNA P02545 2/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
GAA P10253 1/20 0.43
MAPT P10636 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
KDM4E B2RXH2 2/20 0.41
NR1H4 Q96RI1 1/20 0.40
HTT P42858 1/20 0.40
PSMD14 O00487 1/20 0.40
HPGD P15428 1/20 0.40
CRHBP P24387 1/20 0.40
CRHR2 Q13324 1/20 0.40
NR1I2 O75469 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6159022 0.84 MEN1 (0.64) ALDH1A1POLBMEN1KMT2ARAB9A
SCHEMBL10962508 0.84 MEN1 (0.64) ALDH1A1POLBMEN1KMT2ARAB9A
SCHEMBL319887 0.75 ALDH1A1 (0.67) ALDH1A1POLBMEN1KMT2ARAB9A
SCHEMBL7663086 0.74 ALDH1A1 (0.61) ALDH1A1POLBMEN1KMT2ARAB9A
SCHEMBL9487628 0.72 MEN1 (0.64) ALDH1A1POLBMEN1KMT2ARAB9A
SCHEMBL9487630 0.72 MEN1 (0.64) ALDH1A1POLBMEN1KMT2ARAB9A
SCHEMBL7663088 0.72 RAB9A (0.63) ALDH1A1POLBKMT2ARAB9ANPC1
SCHEMBL10716015 0.72 MEN1 (0.68) ALDH1A1POLBMEN1KMT2ARAB9A
SCHEMBL3597213 0.71 ALDH1A1 (1.00) ALDH1A1POLBMEN1KMT2ARAB9A
SCHEMBL3597216 0.71 ALDH1A1 (1.00) ALDH1A1POLBMEN1KMT2ARAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1834977-B1 OPTICAL REFRACTIVE INDEX-MODIFYING POLYMER COMPOSITION, HOLOGRAPHIC RECORDING MATERIAL AND METHOD OF CONTROLLING REFRACTIVE INDEX NITTO DENKO CORP (JP) 2013-08-21 EP disclosed
US-7727679-B2 Optical refractive index-modifying polymer composition, hologram recording material and method of controlling refractive index NITTO DENKO CORPORATION (JP) 2010-06-01 US disclosed
EP-1834977-A1 OPTICAL REFRACTIVE INDEX-MODIFYING POLYMER COMPOSITION, HOLOGRAM RECORDING MATERIAL AND METHOD OF CONTROLLING REFRACTIVE INDEX NITTO DENKO CORPORATION (JP) 2007-09-19 EP disclosed
US-20070128523-A1 Optical refractive index-modifying polymer composition, hologram recording material and method of controlling refractive index NITTO DENKO CORPORATION (JP) 2007-06-07 US disclosed