Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6159743 | 0.74 | CASP1 (0.52) | CASP1 | |
| SCHEMBL6159321 | 0.72 | CASP1 (0.48) | CASP1 | |
| SCHEMBL6159342 | 0.70 | CASP1 (0.60) | CASP1 | |
| SCHEMBL6158852 | 0.69 | CASP1 (0.63) | CASP1 | |
| SCHEMBL6158247 | 0.69 | CASP1 (0.80) | CASP1 | |
| SCHEMBL7420589 | 0.69 | CASP1 (0.51) | CASP1 | |
| SCHEMBL6160210 | 0.69 | CASP1 (0.57) | CASP1 | |
| SCHEMBL6160462 | 0.69 | CASP1 (0.53) | CASP1 | |
| SCHEMBL10348190 | 0.67 | ALDH1A1 (0.59) | — | |
| SCHEMBL6158946 | 0.67 | CASP1 (0.63) | CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1082127-B1 | SUCCINAMIDE INHIBITORS OF INTERLEUKIN-1BETA CONVERTING ENZYME | WARNER LAMBERT CO (US) | 2005-06-22 | — | — | EP | claimed |
| EP-1082127-B1 | SUCCINAMIDE INHIBITORS OF INTERLEUKIN-1BETA CONVERTING ENZYME | WARNER LAMBERT CO (US) | 2005-06-22 | — | — | EP | disclosed |
| EP-1082127-A4 | SUCCINAMIDE INHIBITORS OF INTERLEUKIN-1$g(b) CONVERTING ENZYME | WARNER LAMBERT CO (US) | 2002-10-09 | — | — | EP | disclosed |
| EP-1082127-A1 | SUCCINAMIDE INHIBITORS OF INTERLEUKIN-1$g(b) CONVERTING ENZYME | WARNER-LAMBERT COMPANY (US) | 2001-03-14 | — | — | EP | disclosed |
| WO-1999056765-A1 | SUCCINAMIDE INHIBITORS OF INTERLEUKIN-1β CONVERTING ENZYME | WARNER-LAMBERT COMPANY (US) | 1999-11-11 | — | — | WO | disclosed |