Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8664085 | 0.80 | RAB9A (0.31) | SMN1; SMN2RAB9ATSHR | |
| SCHEMBL10987649 | 0.77 | TSHR (0.50) | SMN1; SMN2HTTPOLBMAPTTDP1 | |
| SCHEMBL14638402 | 0.75 | — | — | |
| SCHEMBL15651754 | 0.72 | POLB (0.50) | HTTPOLBMAPTALDH1A1RECQL | |
| SCHEMBL31716780 | 0.72 | HTR2A (0.36) | SMN1; SMN2HTTPOLBMAPTTDP1 | |
| SCHEMBL22118930 | 0.72 | TSHR (0.34) | SMN1; SMN2HTTPOLBMITFALDH1A1 | |
| SCHEMBL6154188 | 0.71 | CYP1A2 (0.33) | TDP1TSHR | |
| SCHEMBL16975489 | 0.71 | CYP1A2 (0.39) | SMN1; SMN2HTTPOLBMAPTALDH1A1 | |
| SCHEMBL6154539 | 0.71 | HTR2A (0.34) | SMN1; SMN2TSHR | |
| SCHEMBL5021280 | 0.71 | POLB (0.34) | POLBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1580189-A1 | 4-AMINO-5-METHYLPYRAZOLE DERIVATIVES AND PROCESS FOR PRODUCTION THEREOF | Sankyo Agro Company, Limited (JP) | 2005-09-28 | — | — | EP | disclosed |