Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6159480 | 0.80 | SMN1; SMN2 (0.34) | RAB9ASMN1; SMN2TSHR | |
| SCHEMBL10987649 | 0.80 | TSHR (0.50) | RAB9ASMN1; SMN2TSHR | |
| SCHEMBL5161017 | 0.78 | — | — | |
| SCHEMBL15190352 | 0.76 | — | — | |
| SCHEMBL2076292 | 0.76 | PKM (0.51) | — | |
| SCHEMBL2923881 | 0.75 | TSHR (0.34) | TSHR | |
| SCHEMBL6002646 | 0.75 | TSHR (0.34) | TSHR | |
| SCHEMBL22118930 | 0.74 | TSHR (0.34) | SMN1; SMN2TSHR | |
| SCHEMBL2077100 | 0.74 | TSHR (0.54) | RAB9ASMN1; SMN2TSHR | |
| SCHEMBL9228469 | 0.73 | ALDH1A1 (0.36) | RAB9ASMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2628730-B1 | TELESCOPING SYNTHESIS OF 5-AMINO-4-NITROSO-1-ALKYL-1H-PYRAZOLE SALTS | NOXELL CORP (US) | 2017-12-06 | — | — | EP | claimed |
| WO-2013122989-A1 | TELESCOPING SYNTHESIS OF 5-AMINO-4-NITROSO-1-ALKYL-1H-PYRAZOLE SALTS | THE PROCTER & GAMBLE COMPANY (US) | 2013-08-22 | — | — | WO | claimed |
| US-20130217891-A1 | Telescoping Synthesis of 5-Amino-4-Nitroso-1-Alkyl-1H-Pyrazole Salt | THE PROCTER & GAMBLE COMPANY (US) | 2013-08-22 | — | — | US | claimed |
| EP-2628730-A1 | Telescoping synthesis of 5-amino-4-nitroso-1-alkyl-1H-pyrazole salts | The Procter and Gamble Company (US) | 2013-08-21 | — | — | EP | claimed |
| US-5718731-A | Oxidation hair dye composition based on 4,5-diaminopyrazole and m-phenylenediamine derivatives | WELLA AKTIENGESELLSCHAFT (DE) | 1998-02-17 | — | — | US | claimed |
| EP-0692245-B1 | Oxidation hair dye containing 4,5-diaminopyrazole derivatives and m-phenylendiamine derivatives | WELLA AG (DE) | 1997-05-02 | — | — | EP | claimed |
| EP-0692245-A1 | Oxidation hair dye containing 4,5-diaminopyrazole derivatives and m-phenylendiamine derivatives | Wella Aktiengesellschaft (DE) | 1996-01-17 | — | — | EP | claimed |
| JP-8012540-A | — | — | None | — | — | JP | disclosed |
| EP-2628730-B1 | TELESCOPING SYNTHESIS OF 5-AMINO-4-NITROSO-1-ALKYL-1H-PYRAZOLE SALTS | NOXELL CORP (US) | 2017-12-06 | — | — | EP | disclosed |
| CN-104105689-A | Synthesis of 5-amino-4-nitroso-1-alkyl-1H-pyrazole salt by telescoping | PROCTER & GAMBLE | 2014-10-15 | — | — | CN | disclosed |
| US-8785656-B2 | Telescoping synthesis of 5-amino-4-nitroso-1-alkyl-1H-pyrazole salt | THE PROCTER & GAMBLE COMPANY (US) | 2014-07-22 | — | — | US | disclosed |
| US-8785656-B2 | Telescoping synthesis of 5-amino-4-nitroso-1-alkyl-1H-pyrazole salt | THE PROCTER & GAMBLE COMPANY (US) | 2014-07-22 | — | — | US | disclosed |
| WO-2013122989-A1 | TELESCOPING SYNTHESIS OF 5-AMINO-4-NITROSO-1-ALKYL-1H-PYRAZOLE SALTS | THE PROCTER & GAMBLE COMPANY (US) | 2013-08-22 | — | — | WO | disclosed |
| US-20130217891-A1 | Telescoping Synthesis of 5-Amino-4-Nitroso-1-Alkyl-1H-Pyrazole Salt | THE PROCTER & GAMBLE COMPANY (US) | 2013-08-22 | — | — | US | disclosed |
| EP-2628730-A1 | Telescoping synthesis of 5-amino-4-nitroso-1-alkyl-1H-pyrazole salts | The Procter and Gamble Company (US) | 2013-08-21 | — | — | EP | disclosed |
| EP-2628730-A1 | Telescoping synthesis of 5-amino-4-nitroso-1-alkyl-1H-pyrazole salts | The Procter and Gamble Company (US) | 2013-08-21 | — | — | EP | disclosed |
| US-5718731-A | Oxidation hair dye composition based on 4,5-diaminopyrazole and m-phenylenediamine derivatives | WELLA AKTIENGESELLSCHAFT (DE) | 1998-02-17 | — | — | US | disclosed |
| EP-0692245-B1 | Oxidation hair dye containing 4,5-diaminopyrazole derivatives and m-phenylendiamine derivatives | WELLA AG (DE) | 1997-05-02 | — | — | EP | disclosed |
| EP-0692245-A1 | Oxidation hair dye containing 4,5-diaminopyrazole derivatives and m-phenylendiamine derivatives | Wella Aktiengesellschaft (DE) | 1996-01-17 | — | — | EP | disclosed |
| JP-H0812540-A | OXIDATION HAIR DYE COMPOSITION BASED ON 4,5-DIAMINOPYRAZOLE DERIVATIVE AND META-PHENYLENEDIAMINE DERIVATIVE | WELLA AG | 1996-01-16 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130217891-A1 | Telescoping Synthesis of 5-Amino-4-Nitroso-1-Alkyl-1H-Pyrazole Salt | NOX5, PPOX, PAOX | RAB9A 2825/4885SMN1; SMN2 4389/4885TSHR 1296/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.