SCHEMBL6159724

SCHEMBL6159724

CCOC(=O)c1nc(C2CC3C=CC2C3)[nH]c1CCC12CC3CC(CC(C3)C1)C2

nearest known ligand 0.39

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6160311 0.86 EPHX2 (0.38) EPHX2
SCHEMBL6159764 0.86 EPHX2 (0.39) EPHX2
Prochloraz SCHEMBL6159830 0.77 AHR (0.52)
SCHEMBL6162281 0.76
SCHEMBL7688410 0.76
SCHEMBL6163818 0.75 ALOX5 (0.44)
SCHEMBL6160009 0.74 PPARG (0.43)
SCHEMBL6158115 0.73 CCKBR (0.43) EPHX2
SCHEMBL6160216 0.73 CCKBR (0.43) EPHX2
SCHEMBL6159387 0.73 CCKBR (0.43) EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1178969-B1 GASTRIN AND CHOLECYSTOKININ RECEPTOR LIGANDS BLACK JAMES FOUNDATION (GB) 2005-07-13 EP disclosed
US-6479531-B1 Gastrin and cholecystokinin receptor ligands JAMES BLACK FOUNDATION LIMITED (GB) 2002-11-12 US disclosed
EP-1178969-A1 GASTRIN AND CHOLECYSTOKININ RECEPTOR LIGANDS JAMES BLACK FOUNDATION LIMITED (GB) 2002-02-13 EP disclosed
WO-2000027823-A1 GASTRIN AND CHOLECYSTOKININ RECEPTOR LIGANDS JAMES BLACK FOUNDATION LIMITED (GB) 2000-05-18 WO disclosed