SCHEMBL6159752

SCHEMBL6159752

Nc1ccc(CCC(=O)OCc2ccccc2)cc1

nearest known ligand 0.64

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.64
ALDH1A1 P00352 3/20 0.54
MAPK1 P28482 2/20 0.54
L3MBTL1 Q9Y468 2/20 0.54
MAOB P27338 4/20 0.53
MAOA P21397 2/20 0.53
NPC1 O15118 1/20 0.53
RAB9A P51151 1/20 0.53
APP P05067 1/20 0.51
FFAR1 O14842 3/20 0.50
FFAR4 Q5NUL3 1/20 0.50
CASP1 P29466 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9625116 0.91 MAOB (0.56) TDP1ALDH1A1MAPK1L3MBTL1MAOB
SCHEMBL304176 0.90 TDP1 (0.78) TDP1ALDH1A1MAPK1L3MBTL1APP
Bicarbonate SCHEMBL7699565 0.88 TDP1 (0.75) TDP1ALDH1A1MAPK1L3MBTL1APP
SCHEMBL28207503 0.88 TDP1 (0.75) TDP1ALDH1A1MAPK1L3MBTL1APP
Ammonia Solution, Strong SCHEMBL28588274 0.88 TDP1 (0.75) TDP1ALDH1A1MAPK1L3MBTL1APP
SCHEMBL305392 0.87 TDP1 (0.68) TDP1ALDH1A1MAPK1L3MBTL1APP
SCHEMBL3708328 0.85 TDP1 (0.66) TDP1ALDH1A1MAPK1L3MBTL1NPC1
SCHEMBL5450328 0.84 TDP1 (0.56) TDP1ALDH1A1MAPK1L3MBTL1MAOB
SCHEMBL20824921 0.84 TDP1 (0.64) TDP1ALDH1A1MAPK1L3MBTL1APP
SCHEMBL22162624 0.84 TDP1 (0.64) TDP1ALDH1A1MAPK1L3MBTL1APP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116354975-A Compound, solid carrier comprising same and method for preparing nucleic acid 财团法人工业技术研究院 2023-06-30 CN disclosed
US-20230203474-A1 COMPOUND, SOLID CARRIER INCLUDING THE SAME AND METHOD FOR PREPARING NUCLEIC ACID INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2023-06-29 US disclosed
US-20230203474-A1 COMPOUND, SOLID CARRIER INCLUDING THE SAME AND METHOD FOR PREPARING NUCLEIC ACID INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2023-06-29 US disclosed
EP-1178969-B1 GASTRIN AND CHOLECYSTOKININ RECEPTOR LIGANDS BLACK JAMES FOUNDATION (GB) 2005-07-13 EP disclosed
US-6479531-B1 Gastrin and cholecystokinin receptor ligands JAMES BLACK FOUNDATION LIMITED (GB) 2002-11-12 US disclosed
EP-1178969-A1 GASTRIN AND CHOLECYSTOKININ RECEPTOR LIGANDS JAMES BLACK FOUNDATION LIMITED (GB) 2002-02-13 EP disclosed
CN-1325385-A Gastrin and cholecystokinin receptor ligands BLACK JAMES FOUNDATION (GB) 2001-12-05 CN disclosed
WO-2000027823-A1 GASTRIN AND CHOLECYSTOKININ RECEPTOR LIGANDS JAMES BLACK FOUNDATION LIMITED (GB) 2000-05-18 WO disclosed
US-5155268-A Antiarrhythmic N-aminoalkylene alkyl and aryl sulfonamides THE UPJOHN COMPANY (US) 1992-10-13 US disclosed
EP-0164865-B1 N-(AMINOALKYLPHENYL)SULFONAMIDES THEIR PREPARATION AND THERAPEUTIC USE THE UPJOHN COMPANY (US) 1988-12-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230203474-A1 COMPOUND, SOLID CARRIER INCLUDING THE SAME AND METHOD FOR PREPARING NUCLEIC ACID SNRPA, NSUN2, POLRMT TDP1 397/4885ALDH1A1 2601/4885MAPK1 3521/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.