Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | EP300 | Q09472 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6159433 | 0.88 | CCKBR (0.47) | CCKBRADORA3EPHX2 | |
| SCHEMBL6159844 | 0.85 | CCKBR (0.41) | CCKBRADORA3CYP3A4TSHRHSD17B10 | |
| SCHEMBL6159409 | 0.83 | CCKBR (0.46) | CCKBRADORA3EPHX2 | |
| SCHEMBL6158248 | 0.79 | ADORA3 (0.39) | CCKBRADORA3 | |
| SCHEMBL6096321 | 0.78 | CCKBR (0.61) | CCKBRADORA3EPHX2EP300HIF1A | |
| SCHEMBL6159463 | 0.77 | CCKBR (0.64) | CCKBR | |
| SCHEMBL6158930 | 0.76 | CCKBR (0.41) | CCKBRADORA3EPHX2CYP3A4TSHR | |
| SCHEMBL6160311 | 0.72 | EPHX2 (0.38) | EPHX2 | |
| SCHEMBL6096327 | 0.71 | CCKBR (0.43) | CCKBRADORA3EPHX2EP300HIF1A | |
| SCHEMBL6159001 | 0.70 | CCKBR (0.51) | CCKBREPHX2CYP3A4ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1178969-B1 | GASTRIN AND CHOLECYSTOKININ RECEPTOR LIGANDS | BLACK JAMES FOUNDATION (GB) | 2005-07-13 | — | — | EP | disclosed |
| US-6479531-B1 | Gastrin and cholecystokinin receptor ligands | JAMES BLACK FOUNDATION LIMITED (GB) | 2002-11-12 | — | — | US | disclosed |
| EP-1178969-A1 | GASTRIN AND CHOLECYSTOKININ RECEPTOR LIGANDS | JAMES BLACK FOUNDATION LIMITED (GB) | 2002-02-13 | — | — | EP | disclosed |
| WO-2000027823-A1 | GASTRIN AND CHOLECYSTOKININ RECEPTOR LIGANDS | JAMES BLACK FOUNDATION LIMITED (GB) | 2000-05-18 | — | — | WO | disclosed |