Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALCRL | Q16602 | 14/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.52 |
| ▸ | RAMP1 | O60894 | 1/20 | 0.48 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.46 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL6165360 | 0.98 | CALCRL (0.56) | CALCRLCYP3A4RAMP1HSD11B1LMNA | |
| SCHEMBL6161820 | 0.90 | CALCRL (0.58) | CALCRLCYP3A4RAMP1HSD11B1LMNA | |
| SCHEMBL6162042 | 0.90 | CALCRL (0.58) | CALCRLCYP3A4RAMP1HSD11B1LMNA | |
| Trifluoroacetic Acid SCHEMBL6161823 | 0.86 | CALCRL (0.53) | CALCRLCYP3A4HSD11B1LMNAMAPK1 | |
| Trifluoroacetic Acid SCHEMBL6162047 | 0.86 | CALCRL (0.53) | CALCRLCYP3A4HSD11B1LMNAMAPK1 | |
| SCHEMBL6161677 | 0.85 | CALCRL (0.57) | CALCRLCYP3A4RAMP1HSD11B1CHRM2 | |
| SCHEMBL6163603 | 0.85 | CALCRL (0.59) | CALCRLCYP3A4RAMP1HSD11B1 | |
| SCHEMBL6161636 | 0.85 | CALCRL (0.59) | CALCRLCYP3A4RAMP1HSD11B1 | |
| Hydrochloric Acid SCHEMBL6160811 | 0.84 | CALCRL (0.58) | CALCRLCYP3A4RAMP1HSD11B1 | |
| Hydrochloric Acid SCHEMBL6161941 | 0.84 | CALCRL (0.58) | CALCRLCYP3A4RAMP1HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0828754-B1 | DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE | PFIZER (US) | 2005-02-02 | — | — | EP | claimed |