Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.55 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6160325 | 0.89 | HDAC1 (0.58) | KEAP1FFAR1HDAC2HDAC8HDAC6 | |
| SCHEMBL6161301 | 0.87 | MAPT (0.58) | HDAC2HDAC8HDAC6TDP1HDAC1 | |
| SCHEMBL3567707 | 0.83 | KEAP1 (0.53) | KEAP1FFAR1ALDH1A1HDAC2HDAC8 | |
| SCHEMBL1357419 | 0.80 | CES1 (0.52) | FFAR1ALDH1A1HDAC8HDAC6KMT2A | |
| SCHEMBL16519727 | 0.78 | KEAP1 (0.61) | KEAP1FFAR1ALDH1A1HDAC2HDAC8 | |
| SCHEMBL16562278 | 0.78 | F2RL1 (0.58) | FFAR1ALDH1A1TDP1SMN1; SMN2L3MBTL1 | |
| SCHEMBL5429609 | 0.77 | KEAP1 (0.55) | KEAP1FFAR1ALDH1A1HDAC2HDAC8 | |
| SCHEMBL16908259 | 0.76 | KEAP1 (0.59) | KEAP1FFAR1ALDH1A1HDAC2HDAC8 | |
| SCHEMBL2487165 | 0.76 | ALDH1A1 (0.61) | KEAP1FFAR1ALDH1A1HDAC2HDAC8 | |
| SCHEMBL1563454 | 0.74 | KEAP1 (0.61) | KEAP1FFAR1ALDH1A1HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0893442-B1 | LYMPH-ABSORBABLE IMIDAZOLE DERIVATIVES | SHIONOGI & CO (JP) | 2005-01-12 | — | — | EP | disclosed |
| US-6054591-A | LYMPHOTROPIC ANTI-AIDS AGENT | SHIONOGI & CO., LTD. (JP) | 2000-04-25 | — | — | US | disclosed |
| EP-0893442-A1 | LYMPH-ABSORBABLE IMIDAZOLE DERIVATIVES | SHIONOGI & CO., LTD. (JP) | 1999-01-27 | — | — | EP | disclosed |
| US-4992464-A | Bronchodilator, antiinflammatory, antiarthritic, antiallergenic agents | ABBOTT LABORATORIES (US) | 1991-02-12 | — | — | US | disclosed |