Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 4/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.31 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.31 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.31 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.31 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.31 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6160798 | 1.00 | GSK3B (0.33) | GSK3BPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL6162039 | 1.00 | GSK3B (0.33) | GSK3BPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL6159786 | 1.00 | GSK3B (0.33) | GSK3BPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL6162169 | 0.90 | HPGD (0.33) | GSK3B | |
| SCHEMBL8009850 | 0.90 | HPGD (0.33) | GSK3B | |
| SCHEMBL6166944 | 0.90 | HPGD (0.33) | GSK3B | |
| SCHEMBL6161220 | 0.90 | HPGD (0.33) | GSK3B | |
| SCHEMBL6168625 | 0.90 | HPGD (0.33) | GSK3B | |
| SCHEMBL6162355 | 0.90 | HPGD (0.33) | GSK3B | |
| SCHEMBL6161087 | 0.88 | P2RX7 (0.39) | PSEN1PSEN2APH1BNCSTNAPH1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0893442-B1 | LYMPH-ABSORBABLE IMIDAZOLE DERIVATIVES | SHIONOGI & CO (JP) | 2005-01-12 | — | — | EP | disclosed |
| US-6054591-A | LYMPHOTROPIC ANTI-AIDS AGENT | SHIONOGI & CO., LTD. (JP) | 2000-04-25 | — | — | US | disclosed |
| EP-0893442-A1 | LYMPH-ABSORBABLE IMIDAZOLE DERIVATIVES | SHIONOGI & CO., LTD. (JP) | 1999-01-27 | — | — | EP | disclosed |