SCHEMBL6159932

SCHEMBL6159932

CC(C)(CN)C(=O)C(Cl)C(=O)Nc1ccccc1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.72
HSP90AA1 P07900 2/20 0.72
GPR55 Q9Y2T6 2/20 0.72
GAA P10253 4/20 0.58
ALDH1A1 P00352 4/20 0.58
ATM Q13315 3/20 0.58
LMNA P02545 1/20 0.58
RAB9A P51151 2/20 0.53
NPC1 O15118 1/20 0.53
MEN1 O00255 5/20 0.46
KMT2A Q03164 5/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
HPGD P15428 2/20 0.46
HTT P42858 1/20 0.46
RXFP1 Q9HBX9 1/20 0.43
POLB P06746 1/20 0.42
MME P08473 1/20 0.41
ACE P12821 1/20 0.41
TAAR1 Q96RJ0 1/20 0.41
MAPK1 P28482 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11382680 0.88 MAPT (0.72) MAPTHSP90AA1GPR55GAAALDH1A1
SCHEMBL11380571 0.85 MAPT (0.67) MAPTHSP90AA1GPR55GAAALDH1A1
SCHEMBL10698727 0.84 MAPT (1.00) MAPTHSP90AA1GPR55GAAALDH1A1
SCHEMBL11278850 0.81 MAPT (0.65) MAPTHSP90AA1GPR55GAAALDH1A1
SCHEMBL9360044 0.80 MAPT (0.49) MAPTHSP90AA1GPR55GAAALDH1A1
Sulfuric Acid SCHEMBL8961927 0.76 MAPT (0.45) MAPTHSP90AA1GPR55GAAALDH1A1
SCHEMBL2222178 0.74 MAPT (1.00) MAPTHSP90AA1GPR55GAAALDH1A1
SCHEMBL9518770 0.73 MAPT (0.72) MAPTHSP90AA1GPR55GAAALDH1A1
SCHEMBL8752426 0.73 MAPT (0.67) MAPTHSP90AA1GPR55GAAALDH1A1
SCHEMBL15228212 0.73 MAPT (0.56) MAPTHSP90AA1GPR55GAAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0711758-B1 Method of manufacturing a 3-substituted-3-oxo-2-halopropionic acid amide compound and method of manufacturing a 3-substituted-3-oxo-2-(5,5-dimethylhydantoin-3-yl) propionic acid amide compound FUJI PHOTO FILM CO LTD (JP) 2005-01-26 EP disclosed
EP-1020450-B1 3-substituted-3-oxo-2-(5,5-dimethylhydantoin-3-yl) propionic acid amide compound and process for preparation thereof FUJI PHOTO FILM CO LTD (JP) 2004-02-11 EP disclosed
EP-1020450-A1 Method of manufacturing a 3-substituted-3-oxo-2-halopropionic acid amide compound and method of manufacturing a 3-substituted-3-oxo-2-(5,5-dimethylhydantoin-3-yl) propionic acid amide compound FUJI PHOTO FILM CO., LTD. (JP) 2000-07-19 EP disclosed
US-5672714-A HALOGENATION WITH 1,3-DIHALO-5,5-DIMETHYLHYDANTOIN FOLLOWED BY REACTION WITH 5,5-DIMETHYLHYDANTOIN AT THE HALOGENATION SITE TO FORM PHOTOGRAPHIC YELLOW COUPLER COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1997-09-30 US disclosed
EP-0711758-A2 Method of manufacturing a 3-substituted-3-oxo-2-halopropionic acid amide compound and method of manufacturing a 3-substituted-3-oxo-2-(5,5-dimethylhydantoin-3-yl) propionic acid amide compound FUJI PHOTO FILM CO., LTD. (JP) 1996-05-15 EP disclosed
US-4525450-A Silver halide color photographic light sensitive material containing a coupler containing at least one of a sulfamoylphenylenesulfonyl, sulfamoylaminophenylenesulfonyl, or sulfoamidophenylenesulfonyl group FUJI PHOTO FILM CO., LTD. (JP) 1985-06-25 US disclosed
US-4289847-A 2-EQUIVALENT YELLOW COUPLER KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1981-09-15 US disclosed
EP-0017833-A1 Colour-photographic recording material containing a yellow coupler Agfa-Gevaert AG (DE) 1980-10-29 EP disclosed
US-4012258-A POLY-FLUORO-ALKYL MAGENTA OR CYAN COUPLER KONISHIROKU PHOTO INDUSTRY CO., LTD. (JA) 1977-03-15 US disclosed