Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 1.00 |
| ▸ | GAA | P10253 | 3/20 | 1.00 |
| ▸ | ATM | Q13315 | 3/20 | 1.00 |
| ▸ | LMNA | P02545 | 2/20 | 1.00 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.69 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.69 |
| ▸ | RAB9A | P51151 | 3/20 | 0.66 |
| ▸ | NPC1 | O15118 | 2/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.58 |
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.55 |
| ▸ | MME | P08473 | 1/20 | 0.54 |
| ▸ | ACE | P12821 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 3/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5947039 | 0.85 | MAPT (0.72) | MAPTALDH1A1GAAATMLMNA | |
| SCHEMBL9518770 | 0.84 | MAPT (0.72) | MAPTALDH1A1GAAATMLMNA | |
| SCHEMBL8752464 | 0.83 | MAPT (0.71) | MAPTALDH1A1GAAATMLMNA | |
| SCHEMBL8930226 | 0.83 | GAA (0.71) | MAPTALDH1A1GAAATMLMNA | |
| SCHEMBL10698727 | 0.81 | MAPT (1.00) | MAPTALDH1A1GAAATMLMNA | |
| SCHEMBL8752461 | 0.81 | MAPT (0.68) | MAPTALDH1A1GAAATMLMNA | |
| SCHEMBL9470686 | 0.81 | MAPT (0.68) | MAPTALDH1A1GAAATMLMNA | |
| SCHEMBL8752426 | 0.80 | MAPT (0.67) | MAPTALDH1A1GAAATMLMNA | |
| SCHEMBL935298 | 0.80 | CYP1A2 (0.68) | MAPTALDH1A1GAAATMLMNA | |
| SCHEMBL2516508 | 0.80 | ALDH1A1 (0.67) | MAPTALDH1A1GAAATMLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115746579-A | Preparation method of high level-dyeing-property-based dye product | 宁夏保隆科技有限公司 | 2023-03-07 | — | — | CN | claimed |
| CN-114195671-A | Asymmetric malonanilide compound and synthesis method thereof | 河南师范大学 | 2022-03-18 | — | — | CN | claimed |
| CN-103613510-B | Simple method for dehalogenating alpha-halogenated compounds | UNIV ZHEJIANG TECHNOLOGY | 2015-05-06 | — | — | CN | claimed |
| CN-103396680-B | Preparation method for producing acid yellow based on acid-free high-temperature diazotization method | ZHEJIANG DAJING CHEMICAL CO LTD | 2014-11-12 | — | — | CN | claimed |
| CN-103613510-A | Simple method for dehalogenating alpha-halogenated compounds | UNIV ZHEJIANG TECHNOLOGY | 2014-03-05 | — | — | CN | claimed |
| CN-103396680-A | Preparation method for producing acid yellow based on acid-free high-temperature diazotization method | ZHEJIANG DAJING CHEMICAL CO LTD | 2013-11-20 | — | — | CN | claimed |
| JP-2006520397-A | — | — | 2006-09-07 | — | — | JP | claimed |
| US-20060142588-A1 | Acetoacetylation of alcohols, thiols and amines in a microreactor | CLARIANT PRODUKTE (DEUTSCHLAND) GMBH (DE) | 2006-06-29 | — | — | US | claimed |
| EP-1613625-A1 | NOVEL FUSED TRIAZOLONES AND THE USES THEREOF | AstraZeneca AB (SE) | 2006-01-11 | — | — | EP | claimed |
| WO-2004081008-A1 | NOVEL FUSED TRIAZOLONES AND THE USES THEREOF | ASTRAZENECA AB (SE) | 2004-09-23 | — | — | WO | claimed |
| WO-1995034529-A1 | PREPARATION OF ALPHA-CHLOROACETOACETANILIDE COMPOUNDS | UNIROYAL CHEMICAL COMPANY, INC. (US) | 1995-12-21 | — | — | WO | claimed |
| US-5442115-A | Chlorination of acetoacetanilide and derivatives in presence of water and organic solvents mixture | UNIROYAL CHEMICAL COMPANY, INC. (US) | 1995-08-15 | — | — | US | claimed |
| US-4064140-A | FROM A CHLOROACETO-ACETANILIDE AND CYANIDE IONS | CIBA-GEIGY CORPORATION (US) | 1977-12-20 | — | — | US | claimed |
| CN-115746579-A | Preparation method of high level-dyeing-property-based dye product | 宁夏保隆科技有限公司 | 2023-03-07 | — | — | CN | disclosed |
| EP-3470472-B1 | NEW METHINE DYES | LANXESS DEUTSCHLAND GMBH (DE) | 2022-12-07 | — | — | EP | disclosed |
| CN-114605764-A | Carrier composition for inorganic fine particle dispersion, inorganic fine particle dispersion slurry composition, and method for producing inorganic fine particle dispersible tablet | 积水化学工业株式会社 | 2022-06-10 | — | — | CN | disclosed |
| US-4042577-A | POLYESTERS, POLYAMIDES, CELLULOSE ACETATES | SANDOZ LTD. (CH) | 1977-08-16 | — | — | US | disclosed |
| US-4033963-A | Naphthoquinone derivatives | SANDOZ LTD. (CH) | 1977-07-05 | — | — | US | disclosed |
| US-4014679-A | HERBICIDES | ROUSSEL-UCLAF (FR) | 1977-03-29 | — | — | US | disclosed |
| US-3931163-A | PIGMENTS, DISPERSE DYES | SANDOZ LTD., (SANDOZ AG) (CH) | 1976-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060142588-A1 | Acetoacetylation of alcohols, thiols and amines in a microreactor | ADH1A, GRHPR, AKR1C2 | MAPT 3116/4885ALDH1A1 48/4885GAA 2995/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.