SCHEMBL10698727

SCHEMBL10698727

CC(C)(C)C(=O)C(Cl)C(=O)Nc1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 1.00
HSP90AA1 P07900 2/20 1.00
GPR55 Q9Y2T6 2/20 1.00
ALDH1A1 P00352 5/20 0.69
GAA P10253 3/20 0.69
ATM Q13315 3/20 0.69
LMNA P02545 1/20 0.69
RAB9A P51151 2/20 0.62
NPC1 O15118 1/20 0.62
MEN1 O00255 5/20 0.54
KMT2A Q03164 5/20 0.54
SMN1; SMN2 Q16637 4/20 0.54
HPGD P15428 2/20 0.54
HTT P42858 2/20 0.54
POLB P06746 2/20 0.50
RXFP1 Q9HBX9 1/20 0.50
NAPRT Q6XQN6 1/20 0.47
HSD17B10 Q99714 1/20 0.47
TP53 P04637 1/20 0.45
EPHX1 P07099 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11382680 0.84 MAPT (0.72) MAPTHSP90AA1GPR55ALDH1A1GAA
SCHEMBL6159932 0.84 MAPT (0.72) MAPTHSP90AA1GPR55ALDH1A1GAA
SCHEMBL9471936 0.84 MAPT (0.73) MAPTHSP90AA1GPR55ALDH1A1GAA
SCHEMBL9471183 0.83 MAPT (0.71) MAPTHSP90AA1GPR55ALDH1A1GAA
SCHEMBL9470930 0.83 MAPT (0.71) MAPTHSP90AA1GPR55ALDH1A1GAA
SCHEMBL9471206 0.83 MAPT (0.71) MAPTHSP90AA1GPR55ALDH1A1GAA
SCHEMBL2222178 0.81 MAPT (1.00) MAPTHSP90AA1GPR55ALDH1A1GAA
SCHEMBL6159935 0.81 MAPT (0.68) MAPTHSP90AA1GPR55ALDH1A1GAA
SCHEMBL9518770 0.81 MAPT (0.72) MAPTHSP90AA1GPR55ALDH1A1GAA
SCHEMBL11380571 0.81 MAPT (0.67) MAPTHSP90AA1GPR55ALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0259864-A2 Silver halide color photographic material FUJI PHOTO FILM CO., LTD. (JP) 1988-03-16 EP disclosed
US-4404274-A Photographic light sensitive element containing yellow color coupler and method for forming yellow photographic images FUJI PHOTO FILM CO., LTD. (JP) 1983-09-13 US disclosed
US-4314023-A AZO-METHINE DYES KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1982-02-02 US disclosed
US-4310618-A Silver halide photographic material and process utilizing blocked dye-forming couplers EASTMAN KODAK COMPANY (US) 1982-01-12 US disclosed
US-4304845-A POLYHYDRIC ALCOHOLS, POLYURETHANE INTERMEDIATES KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1981-12-08 US disclosed
US-4286053-A ALPHA- PIVALOYL ACETANILIDE COUPLERS HAVING A BALLASTING SULFONYL ALKYL AMIDO GROUP; PHOTOSTABILITY; YELLOW KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1981-08-25 US disclosed
US-4071365-A Silver halide emulsion containing two-equivalent yellow dye-forming coupler MITSUBISHI PAPER MILLS, LTD. (JA) 1978-01-31 US disclosed
US-4008086-A PYRIDONE OR PYRIDAZONE DERIVATIVES KONISHIROKU PHOTO INDUSTRY CO., LTD. (JA) 1977-02-15 US disclosed
US-3973968-A YELLOW KONISHIROKU PHOTO INDUSTRY CO., LTD. (JA) 1976-08-10 US disclosed