Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.35 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.35 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.32 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.32 |
| ▸ | MATK | P42679 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | MAPKAPK3 | Q16644 | 1/20 | 0.32 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6160120 | 0.88 | KCNH2 (0.48) | KCNH2POLBCACNA1FMAPK1CACNA1D | |
| SCHEMBL9023245 | 0.83 | POLB (0.48) | KCNH2POLBCACNA1FMAPK1CACNA1D | |
| SCHEMBL7462916 | 0.83 | KCNH2 (0.34) | KCNH2POLBCACNA1FMAPK1CACNA1D | |
| SCHEMBL8007488 | 0.81 | PIM3 (0.41) | KCNH2POLBCACNA1FMAPK1CACNA1D | |
| SCHEMBL15063038 | 0.79 | CACNA1F (0.36) | KCNH2POLBCACNA1FMAPK1CACNA1D | |
| SCHEMBL5787369 | 0.78 | CYP3A4 (0.37) | KCNH2POLBCACNA1FMAPK1CACNA1D | |
| SCHEMBL10443389 | 0.78 | KCNH2 (0.53) | KCNH2POLBCACNA1FMAPK1CACNA1D | |
| SCHEMBL9372414 | 0.78 | KCNH2 (0.53) | KCNH2POLBCACNA1FMAPK1CACNA1D | |
| SCHEMBL6974626 | 0.77 | MEN1 (0.45) | KCNH2POLBCACNA1FMAPK1CACNA1D | |
| SCHEMBL9023000 | 0.76 | KCNH2 (0.50) | KCNH2POLBCACNA1FMAPK1CACNA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0919553-B1 | cis-SUBSTITUTED AMINOCYCLOPROPANE DERIVATIVES | DAIICHI SEIYAKU CO (JP) | 2005-03-02 | — | — | EP | claimed |