Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM3 | Q86V86 | 2/20 | 0.41 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.41 |
| ▸ | MATK | P42679 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | MAPKAPK3 | Q16644 | 1/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | GSK3A | P49840 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.37 |
| ▸ | TOP1 | P11387 | 4/20 | 0.36 |
| ▸ | TOP2A | P11388 | 11/20 | 0.35 |
| ▸ | TOP2B | Q02880 | 9/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8116711 | 0.91 | POLB (0.49) | PIM3RPS6KB1MATKDYRK1AMAPKAPK3 | |
| SCHEMBL10444023 | 0.87 | POLB (0.49) | PIM3RPS6KB1MATKDYRK1AMAPKAPK3 | |
| SCHEMBL8010003 | 0.86 | RPS6KB1 (0.51) | PIM3RPS6KB1MATKDYRK1AMAPKAPK3 | |
| SCHEMBL7997604 | 0.86 | RPS6KB1 (0.51) | PIM3RPS6KB1MATKDYRK1AMAPKAPK3 | |
| SCHEMBL7997606 | 0.86 | RPS6KB1 (0.51) | PIM3RPS6KB1MATKDYRK1AMAPKAPK3 | |
| SCHEMBL7997969 | 0.84 | CYP3A4 (0.34) | POLBCYP3A4KCNH2MEN1KMT2A | |
| SCHEMBL7997798 | 0.84 | KCNH2 (0.45) | PIM3RPS6KB1MATKDYRK1AMAPKAPK3 | |
| SCHEMBL10443387 | 0.83 | MEN1 (0.51) | PIM3RPS6KB1MATKDYRK1AMAPKAPK3 | |
| SCHEMBL10509377 | 0.83 | MEN1 (0.51) | PIM3RPS6KB1MATKDYRK1AMAPKAPK3 | |
| SCHEMBL6160126 | 0.81 | KCNH2 (0.35) | PIM3RPS6KB1MATKDYRK1AMAPKAPK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0593766-B1 | PYRIDONECARBOXYLIC ACID DERIVATIVE | DAIICHI SEIYAKU CO (JP) | 2000-09-06 | — | — | EP | claimed |