Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3821417 | 0.99 | MCOLN3 (0.56) | MCOLN3ALDH1A1SMN1; SMN2TSHRCYP3A4 | |
| SCHEMBL6159541 | 0.86 | KIF18A (0.45) | MCOLN3ALDH1A1SMN1; SMN2KDM4ELMNA | |
| SCHEMBL6159851 | 0.86 | EPHX2 (0.46) | MCOLN3ALDH1A1SMN1; SMN2GAAMEN1 | |
| Hydrochloric Acid SCHEMBL3818307 | 0.85 | KIF18A (0.44) | MCOLN3ALDH1A1SMN1; SMN2KDM4ELMNA | |
| Hydrochloric Acid SCHEMBL3814238 | 0.85 | EPHX2 (0.45) | MCOLN3ALDH1A1SMN1; SMN2GAAMEN1 | |
| SCHEMBL6160034 | 0.83 | SMN1; SMN2 (0.46) | MCOLN3ALDH1A1SMN1; SMN2CYP3A4MEN1 | |
| SCHEMBL3835927 | 0.83 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2MEN1KMT2APKM | |
| Hydrochloric Acid SCHEMBL3812575 | 0.82 | SMN1; SMN2 (0.46) | MCOLN3ALDH1A1SMN1; SMN2CYP3A4MEN1 | |
| Hydrochloric Acid SCHEMBL3821830 | 0.81 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2MEN1KMT2APKM | |
| SCHEMBL10739716 | 0.76 | MCOLN3 (0.74) | MCOLN3ALDH1A1SMN1; SMN2TSHRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1470114-A4 | PEPTIDE NUCLEIC ACID OLIGOMERS FROM 1-BENZENESULFONYL-3-AMINO ACID SIDE CHAIN-4-(2-NUCLEOBASE(ACETYL))-PIPERAZIN-2-ONES | PANAGENE INC (KR) | 2005-05-11 | — | — | EP | disclosed |
| EP-1470114-A1 | PEPTIDE NUCLEIC ACID OLIGOMERS FROM 1-BENZENESULFONYL-3-AMINO ACID SIDE CHAIN-4-(2-NUCLEOBASE(ACETYL))-PIPERAZIN-2-ONES | Panagene, Inc. (KR) | 2004-10-27 | — | — | EP | disclosed |
| WO-2003062212-A1 | PEPTIDE NUCLEIC ACID OLIGOMERS FROM 1-BENZENESULFONYL-3-AMINO ACID SIDE CHAIN-4-(2-NUCLEOBASE(ACETYL))-PIPERAZIN-2-ONES | PANAGENE, INC. (US) | 2003-07-31 | — | — | WO | disclosed |