Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.76 |
| ▸ | ESR1 | P03372 | 3/20 | 0.57 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | HTR2C | P28335 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | SPR | P35270 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | PNMT | P11086 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18701651 | 0.89 | PKM (0.60) | PKMALDH1A1HPGDHSD17B10HTR2C | |
| SCHEMBL4394801 | 0.85 | ALDH1A1 (0.60) | PKMALDH1A1HPGDHSD17B10HTR2C | |
| SCHEMBL2993408 | 0.83 | ESR1 (0.68) | PKMESR1ESR2HPGDLMNA | |
| SCHEMBL11477876 | 0.82 | ESR1 (0.67) | PKMESR1ESR2HPGDLMNA | |
| SCHEMBL30408119 | 0.81 | ESR1 (0.65) | PKMESR1ESR2HPGDLMNA | |
| SCHEMBL20681402 | 0.81 | ESR1 (0.65) | PKMESR1ESR2PNMT | |
| SCHEMBL490066 | 0.81 | ESR1 (0.65) | PKMESR1ESR2HPGDLMNA | |
| SCHEMBL30770403 | 0.81 | ESR1 (0.65) | PKMESR1ESR2PNMT | |
| SCHEMBL8277232 | 0.81 | ESR1 (0.65) | PKMESR1ESR2PNMT | |
| SCHEMBL25730136 | 0.81 | PKM (0.62) | PKMESR1ESR2ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0828754-B1 | DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE | PFIZER (US) | 2005-02-02 | — | — | EP | disclosed |