Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | STS | P08842 | 5/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8996649 | 0.90 | KMT2A (0.44) | KMT2APOLBMAPTNPC1SMN1; SMN2 | |
| SCHEMBL11738975 | 0.89 | POLB (0.55) | KMT2APOLBMAPTNPC1SMN1; SMN2 | |
| SCHEMBL11078052 | 0.88 | NPC1 (0.57) | KMT2APOLBMAPTNPC1LMNA | |
| SCHEMBL9505174 | 0.88 | MAPT (0.56) | KMT2AMAPTLMNAALDH1A1HTT | |
| SCHEMBL10915831 | 0.87 | MAPT (0.45) | KMT2APOLBMAPTNPC1SMN1; SMN2 | |
| SCHEMBL11528622 | 0.86 | MAPT (0.54) | KMT2AMAPTNPC1SMN1; SMN2HDAC6 | |
| SCHEMBL11315193 | 0.84 | ALDH1A1 (0.56) | KMT2APOLBMAPTNPC1SMN1; SMN2 | |
| SCHEMBL10506555 | 0.83 | MAPT (0.49) | KMT2APOLBMAPTNPC1SMN1; SMN2 | |
| SCHEMBL10939929 | 0.82 | MAPT (0.48) | KMT2APOLBMAPTNPC1SMN1; SMN2 | |
| SCHEMBL11636039 | 0.82 | NPC1 (0.51) | KMT2AMAPTNPC1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711758-B1 | Method of manufacturing a 3-substituted-3-oxo-2-halopropionic acid amide compound and method of manufacturing a 3-substituted-3-oxo-2-(5,5-dimethylhydantoin-3-yl) propionic acid amide compound | FUJI PHOTO FILM CO LTD (JP) | 2005-01-26 | — | — | EP | disclosed |
| EP-1020450-A1 | Method of manufacturing a 3-substituted-3-oxo-2-halopropionic acid amide compound and method of manufacturing a 3-substituted-3-oxo-2-(5,5-dimethylhydantoin-3-yl) propionic acid amide compound | FUJI PHOTO FILM CO., LTD. (JP) | 2000-07-19 | — | — | EP | disclosed |
| US-5672714-A | HALOGENATION WITH 1,3-DIHALO-5,5-DIMETHYLHYDANTOIN FOLLOWED BY REACTION WITH 5,5-DIMETHYLHYDANTOIN AT THE HALOGENATION SITE TO FORM PHOTOGRAPHIC YELLOW COUPLER COMPOUND | FUJI PHOTO FILM CO., LTD. (JP) | 1997-09-30 | — | — | US | disclosed |
| EP-0711758-A2 | Method of manufacturing a 3-substituted-3-oxo-2-halopropionic acid amide compound and method of manufacturing a 3-substituted-3-oxo-2-(5,5-dimethylhydantoin-3-yl) propionic acid amide compound | FUJI PHOTO FILM CO., LTD. (JP) | 1996-05-15 | — | — | EP | disclosed |
| US-4824773-A | NOVEL YELLOW COUPLERS | FUJI PHOTO FILM CO., LTD. (JP) | 1989-04-25 | — | — | US | disclosed |
| US-4326024-A | Silver halide emulsion containing yellow-dye-forming coupler | FUJI PHOTO FILM CO., LTD. (JP) | 1982-04-20 | — | — | US | disclosed |