SCHEMBL9505174

SCHEMBL9505174

CCCCCCCCCCCCOc1ccc(C(=O)CC(=O)Nc2cc(C(=O)OC)ccc2Cl)cc1

nearest known ligand 0.56

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.56
ALDH1A1 P00352 6/20 0.51
TSHR P16473 2/20 0.50
TP53 P04637 1/20 0.47
KDM4E B2RXH2 1/20 0.47
HPGD P15428 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
THRA P10827 3/20 0.46
THRB P10828 3/20 0.46
PLA2G4B P0C869 1/20 0.46
MMP1 P03956 1/20 0.46
HTT P42858 3/20 0.45
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
LMNA P02545 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9503267 0.88 MAPT (0.60) MAPTALDH1A1TSHRTP53LMNA
SCHEMBL6160733 0.88 KMT2A (0.54) MAPTALDH1A1KDM4EHPGDL3MBTL1
SCHEMBL10599913 0.85 PLA2G4B (0.51) MAPTALDH1A1TSHRTP53L3MBTL1
SCHEMBL10915831 0.83 MAPT (0.45) MAPTALDH1A1TSHRKDM4EHTT
SCHEMBL9509058 0.82 MAPT (0.56) MAPTALDH1A1TSHRTP53KDM4E
SCHEMBL8996649 0.82 KMT2A (0.44) MAPTALDH1A1TSHRKDM4EHPGD
SCHEMBL11078052 0.81 NPC1 (0.57) MAPTALDH1A1TSHRHTTMEN1
SCHEMBL2356406 0.80 MAPT (0.66) MAPTTSHRTP53THRATHRB
SCHEMBL2355796 0.80 MAPT (0.66) MAPTTSHRTP53THRATHRB
SCHEMBL2756458 0.80 MAPT (0.63) MAPTALDH1A1TSHRKDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0296793-B1 COLOUR PHOTOGRAPHIC SILVER HALIDE MATERIALS AND PROCESS EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1993-08-25 EP disclosed