⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dimethylformamide SCHEMBL9464389 | 0.75 | TSHR (0.47) | — | |
| SCHEMBL613870 | 0.74 | LMNA (0.34) | — | |
| SCHEMBL616450 | 0.74 | LMNA (0.36) | — | |
| Dimethylformamide SCHEMBL314310 | 0.73 | LMNA (0.60) | — | |
| SCHEMBL11728019 | 0.73 | — | — | |
| SCHEMBL177621 | 0.72 | — | — | |
| SCHEMBL10717030 | 0.71 | LMNA (0.47) | — | |
| SCHEMBL3395781 | 0.71 | — | — | |
| SCHEMBL21039925 | 0.70 | LMNA (0.32) | — | |
| Dimethylformamide SCHEMBL131192 | 0.70 | LMNA (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10696622-B2 | Synthesis of N-vinyl carboxylic acid amides | EASTMAN CHEMICAL COMPANY (US) | 2020-06-30 | — | — | US | disclosed |
| EP-3504184-A1 | SYNTHESIS OF 1-HYDROXYETHYL FORMAMIDES AND N-VINYL FORMAMIDES | Taminco BVBA (BE) | 2019-07-03 | — | — | EP | disclosed |
| WO-2018041615-A1 | SYNTHESIS OF 1-HYDROXYETHYL FORMAMIDES AND N-VINYL FORMAMIDES | TAMINCO BVBA (BE) | 2018-03-08 | — | — | WO | disclosed |
| US-20180057445-A1 | SYNTHESIS OF N-VINYL CARBOXYLIC ACID AMIDES | TAMINCO BVBA (BE) | 2018-03-01 | — | — | US | disclosed |
| US-8466287-B2 | Process for producing tricyclic ketone | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 2013-06-18 | — | — | US | disclosed |
| US-20120041204-A1 | PROCESS FOR PRODUCING TRICYCLIC KETONE | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 2012-02-16 | — | — | US | disclosed |
| US-8067595-B2 | Process for producing tricyclic ketone | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 2011-11-29 | — | — | US | disclosed |
| US-20090023927-A1 | Process for producing tricyclic ketone | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 2009-01-22 | — | — | US | disclosed |
| EP-1900740-A1 | PROCESS FOR PRODUCING TRICYCLIC KETONE | Kabushiki Kaisha Yakult Honsha (JP) | 2008-03-19 | — | — | EP | disclosed |