SCHEMBL6160838

SCHEMBL6160838

O=CC(C1CCCCC1)C1CCCCC1

nearest known ligand 0.42

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ADH1A P07327 5/20 0.42
ADH1C P00326 4/20 0.42
ADH1B P00325 3/20 0.42
ADH4 P08319 1/20 0.42
EPHX1 P07099 2/20 0.39
ADH7 P40394 1/20 0.38
SHBG P04278 1/20 0.36
TP53 P04637 1/20 0.33
KDM4E B2RXH2 1/20 0.32
GMNN O75496 1/20 0.32
LMNA P02545 1/20 0.32
MAPT P10636 1/20 0.32
BLM P54132 1/20 0.32
PMP22 Q01453 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8794444 0.84
SCHEMBL1702118 0.81 CPN1 (0.34) ADH1AADH1CADH1BADH4EPHX1
SCHEMBL11220305 0.73 ADH1A (0.39) ADH1AADH1CADH1BADH4EPHX1
SCHEMBL5646568 0.72 EPHX1 (0.41) ADH1AADH1CADH1BADH4EPHX1
SCHEMBL21114321 0.72 ADH1A (0.41) ADH1AADH1CADH1BADH4EPHX1
SCHEMBL11225403 0.72 ADH1A (0.39) ADH1AADH1CADH1BADH4EPHX1
SCHEMBL21114287 0.72 ADH1A (0.41) ADH1AADH1CADH1BADH4EPHX1
SCHEMBL22081103 0.72 EPHX1 (0.41) ADH1AADH1CADH1BADH4EPHX1
SCHEMBL21114234 0.72 ADH1A (0.41) ADH1AADH1CADH1BADH4EPHX1
SCHEMBL5275950 0.72 ADH1A (0.39) ADH1AADH1CADH1BADH4EPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103086848-B Dicyclohexylalkyl ether terminal olefines liquid crystal compound and preparation method thereof YANTAI DERUN LIQUID CRYSTAL MATERIALS CO LTD 2014-09-03 CN claimed
CN-103086848-A Dicyclohexylalkyl ether terminal olefines liquid crystal compound and preparation method thereof YANTAI DERUN LIQUID CRYSTAL MATERIALS CO LTD 2013-05-08 CN claimed
CN-119118864-A RXFP1 receptor agonist and preparation method and medical application thereof 深圳信立泰药业股份有限公司 2024-12-13 CN disclosed
CN-118619931-A Aryl or heteroaryl derivative inhibitor, preparation method and application thereof 上海翰森生物医药科技有限公司 2024-09-10 CN disclosed
CN-118317962-A Imidazopyridazine IL-17 inhibitor compounds 詹森药业有限公司 2024-07-09 CN disclosed
CN-114585628-B Modulators of cystic fibrosis transmembrane conductance regulator 弗特克斯药品有限公司 2024-03-26 CN disclosed
CN-111295382-B Bridged bicyclic compounds as farnesyl ester X receptor modulators 百时美施贵宝公司 2024-02-02 CN disclosed
CN-117285547-A Macrocyclic compounds as modulators of CFTR, pharmaceutical compositions thereof, their use and methods of preparation 弗特克斯药品有限公司 2023-12-26 CN disclosed
CN-111278821-B Spiro compounds as farnesol X receptor modulators 百时美施贵宝公司 2023-10-03 CN disclosed
CN-116583521-A Imidazopyridazine derivatives as IL-17 modulators UCB生物制药有限责任公司 2023-08-11 CN disclosed
CN-116406267-A Bicyclic propyl methyl derivatives as IL-17 modulators UCB生物制药有限责任公司 2023-07-07 CN disclosed
EP-1178969-A1 GASTRIN AND CHOLECYSTOKININ RECEPTOR LIGANDS JAMES BLACK FOUNDATION LIMITED (GB) 2002-02-13 EP disclosed
CN-1325385-A Gastrin and cholecystokinin receptor ligands BLACK JAMES FOUNDATION (GB) 2001-12-05 CN disclosed
EP-0637623-B1 Cyclic hydrocarbon derivative and liquid crystal composition containing the same DAINIPPON INK & CHEMICALS (JP) 2001-10-04 EP disclosed
WO-2000027823-A1 GASTRIN AND CHOLECYSTOKININ RECEPTOR LIGANDS JAMES BLACK FOUNDATION LIMITED (GB) 2000-05-18 WO disclosed
EP-1000924-A1 ACID-SENSITIVE COMPOUND AND RESIN COMPOSITION FOR PHOTORESIST Daichel Chemical Industries Ltd (JP) 2000-05-17 EP disclosed
US-5536443-A DUTERIUM CONTAINING COMPOUNDS FOOR ELECTROOPTICAL APPARATUS DAINIPPON INK & CHEMICALS, INC. (JP) 1996-07-16 US disclosed
US-5474707-A Electrooptic display DAINIPPON INK AND CHEMICALS, INC. (JP) 1995-12-12 US disclosed
EP-0637623-A1 Cyclic hydrocarbon derivative and liquid crystal composition containing the same DAINIPPON INK AND CHEMICALS, INC. (JP) 1995-02-08 EP disclosed
US-4370323-A 2-Cyanoaziridinyl-(1)-2-substituted-aziridinyl-(1)-methanes BOEHRINGER MANNHEIM GMBH (DE) 1983-01-25 US disclosed