Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1A | P07327 | 5/20 | 0.39 |
| ▸ | ADH1C | P00326 | 4/20 | 0.39 |
| ▸ | ADH1B | P00325 | 3/20 | 0.39 |
| ▸ | ADH4 | P08319 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.36 |
| ▸ | ADH7 | P40394 | 1/20 | 0.35 |
| ▸ | SHBG | P04278 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | GMNN | O75496 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15884295 | 0.97 | — | — | |
| SCHEMBL1496437 | 0.86 | — | — | |
| SCHEMBL23727310 | 0.86 | — | — | |
| SCHEMBL1835561 | 0.78 | ALDH1A1 (0.30) | — | |
| Hydrochloric Acid SCHEMBL23727291 | 0.77 | CPN1 (0.31) | — | |
| SCHEMBL2490253 | 0.75 | MAPT (0.35) | MAPT | |
| SCHEMBL1838306 | 0.75 | — | — | |
| SCHEMBL22497888 | 0.75 | MAPT (0.35) | MAPT | |
| SCHEMBL6160838 | 0.72 | ADH1A (0.42) | ADH1AADH1CADH1BADH4EPHX1 | |
| SCHEMBL1647134 | 0.72 | NCF1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4321372-A | Antiulcer thiazol-2-ylcarbamoyl-carboxylic acids, esters and amides | PFIZER INC. (US) | 1982-03-23 | — | — | US | disclosed |
| US-3931331-A | PLANT PROTECTION INTERMEDIATES | ALLIED CHEMICAL CORPORATION (US) | 1976-01-06 | — | — | US | disclosed |