Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 18/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 2/20 | 0.41 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.41 |
| ▸ | PLG | P00747 | 1/20 | 0.41 |
| ▸ | PLAT | P00750 | 1/20 | 0.41 |
| ▸ | PROC | P04070 | 1/20 | 0.41 |
| ▸ | HPN | P05981 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.41 |
| ▸ | NQO2 | P16083 | 1/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.41 |
| ▸ | SLC47A2 | Q86VL8 | 1/20 | 0.41 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6165313 | 0.87 | F2 (0.58) | F2HDAC1HDAC8 | |
| SCHEMBL6162892 | 0.79 | F2 (0.53) | F2HDAC1F10PLGNQO2 | |
| Hydrochloric Acid SCHEMBL6161320 | 0.76 | F2 (0.53) | F2 | |
| SCHEMBL7252982 | 0.74 | F2 (0.68) | F2F10SLC22A2PLGPLAT | |
| SCHEMBL23901812 | 0.74 | F2 (0.57) | F2PLG | |
| SCHEMBL34433937 | 0.74 | F2 (0.57) | F2PLG | |
| SCHEMBL7251622 | 0.74 | F2 (0.60) | F2HDAC1 | |
| Hydrochloric Acid SCHEMBL7249776 | 0.74 | F2 (0.62) | F2HDAC1HDAC8F10 | |
| Hydrochloric Acid SCHEMBL7251642 | 0.74 | F2 (0.67) | F2F10SLC22A2PLGPLAT | |
| Hydrochloric Acid SCHEMBL7246548 | 0.74 | F2 (0.59) | F2HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1210335-B1 | AMINOCARBONYL-SUBSTITUTED BENZIMIDAZOLE DERIVATIVES, METHOD FOR PRODUCING SAME AND THE USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA (DE) | 2005-09-14 | — | — | EP | disclosed |