Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 11/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6162892 | 0.89 | F2 (0.53) | F2HDAC6HDAC1ITGB3ITGA2B | |
| SCHEMBL6160850 | 0.87 | F2 (0.56) | F2HDAC1HDAC8 | |
| SCHEMBL7251622 | 0.79 | F2 (0.60) | F2HDAC6HDAC1 | |
| Hydrochloric Acid SCHEMBL7249776 | 0.79 | F2 (0.62) | F2HDAC6HDAC1HDAC8 | |
| Hydrochloric Acid SCHEMBL7246548 | 0.79 | F2 (0.59) | F2HDAC6HDAC1 | |
| SCHEMBL9252732 | 0.78 | HDAC1 (0.46) | HDAC6HDAC1HDAC8ITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL6476029 | 0.78 | F2 (0.53) | F2HDAC6 | |
| Hydrochloric Acid SCHEMBL7248124 | 0.78 | F2 (0.62) | F2HDAC6 | |
| SCHEMBL9250758 | 0.77 | HDAC6 (0.52) | F2HDAC6HDAC1HDAC8ITGB3 | |
| Hydrochloric Acid SCHEMBL6161320 | 0.77 | F2 (0.53) | F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1210335-B1 | AMINOCARBONYL-SUBSTITUTED BENZIMIDAZOLE DERIVATIVES, METHOD FOR PRODUCING SAME AND THE USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA (DE) | 2005-09-14 | — | — | EP | disclosed |