Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 13/20 | 0.53 |
| ▸ | F10 | P00742 | 4/20 | 0.47 |
| ▸ | PLG | P00747 | 2/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.43 |
| ▸ | NQO2 | P16083 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6165313 | 0.89 | F2 (0.58) | F2ITGB3ITGA2BHDAC6HDAC1 | |
| SCHEMBL6162641 | 0.87 | CTSG (0.45) | F2HDAC6HDAC1 | |
| SCHEMBL7244531 | 0.82 | F2 (0.58) | F2F10PLGNQO2 | |
| SCHEMBL6162574 | 0.80 | F2 (0.52) | F2F10PLGNQO2HDAC6 | |
| SCHEMBL6160850 | 0.79 | F2 (0.56) | F2F10PLGNQO2HDAC1 | |
| Hydrochloric Acid SCHEMBL8026991 | 0.77 | F2 (0.54) | F2F10PLGNQO2PPARG | |
| SCHEMBL7369551 | 0.76 | F10 (0.55) | F2F10PLGNQO2 | |
| Hydrochloric Acid SCHEMBL7252029 | 0.75 | F2 (0.61) | F2F10PLGNQO2 | |
| SCHEMBL7251622 | 0.75 | F2 (0.60) | F2HDAC6HDAC1 | |
| Hydrochloric Acid SCHEMBL6476029 | 0.75 | F2 (0.53) | F2F10HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1210335-B1 | AMINOCARBONYL-SUBSTITUTED BENZIMIDAZOLE DERIVATIVES, METHOD FOR PRODUCING SAME AND THE USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA (DE) | 2005-09-14 | — | — | EP | disclosed |
| US-6512000-B1 | Aminocarbonyl- substituted benzimidazole derivatives for the treatment of diseases in which inhibition of tryptase is of therapeutic such as for treating an inflammatory or allergic disease | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2003-01-28 | — | — | US | disclosed |
| EP-1210335-A1 | AMINOCARBONYL-SUBSTITUTED BENZIMIDAZOLE DERIVATIVES, METHOD FOR PRODUCING SAME AND THE USE THEREOF AS MEDICAMENTS | Boehringer Ingelheim Pharma KG (DE) | 2002-06-05 | — | — | EP | disclosed |
| WO-2001014342-A1 | AMINOCARBONYL-SUBSTITUTED BENZIMIDAZOLE DERIVATIVES, METHOD FOR PRODUCING SAME AND THE USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2001-03-01 | — | — | WO | disclosed |