Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR2 | P21452 | 6/20 | 0.62 |
| ▸ | TACR1 | P25103 | 3/20 | 0.62 |
| ▸ | TACR3 | P29371 | 6/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7988071 | 0.85 | TACR2 (0.61) | TACR2TACR1TACR3 | |
| Hydrochloric Acid SCHEMBL6161088 | 0.85 | TACR2 (0.61) | TACR2TACR1TACR3 | |
| SCHEMBL14089179 | 0.82 | TACR2 (0.75) | TACR2TACR1TACR3 | |
| SCHEMBL7870009 | 0.81 | TACR2 (0.73) | TACR2TACR1TACR3 | |
| SCHEMBL6952599 | 0.81 | TACR2 (0.73) | TACR2TACR1TACR3 | |
| SCHEMBL6950366 | 0.80 | TACR2 (0.67) | TACR2TACR1TACR3 | |
| SCHEMBL7870048 | 0.79 | TACR2 (0.67) | TACR2TACR1TACR3 | |
| SCHEMBL6588311 | 0.79 | TACR2 (0.69) | TACR2TACR1TACR3 | |
| SCHEMBL6033897 | 0.77 | TACR2 (0.64) | TACR2TACR1TACR3 | |
| SCHEMBL7312636 | 0.77 | TACR2 (0.66) | TACR2TACR1TACR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0739891-B1 | Substituted heterocycles | ASTRAZENECA AB (SE) | 2005-01-19 | — | — | EP | disclosed |
| US-6355695-B1 | ANTIHISTAMINES; ASTHMA THERAPY | ZENECA LIMITED (SE) | 2002-03-12 | — | — | US | disclosed |
| US-6235757-B1 | ANTIHISTAMINES | ZENECA LIMITED (GB) | 2001-05-22 | — | — | US | disclosed |
| US-6051580-A | Substituted heterocycles | ZENECA LIMITED | 2000-04-18 | — | — | US | disclosed |
| EP-0739891-A2 | Substituted heterocycles | ZENECA LIMITED (GB) | 1996-10-30 | — | — | EP | disclosed |