Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPIA | P62937 | 2/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | CCKBR | P32239 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7087125 | 0.92 | PPIA (0.43) | PPIACCKBRRAB9A | |
| SCHEMBL7083915 | 0.86 | NPC1 (0.37) | EPHX2RAB9A | |
| SCHEMBL6157991 | 0.83 | EPHX2 (0.35) | EPHX2 | |
| SCHEMBL6330062 | 0.82 | EPHX2 (0.37) | EPHX2 | |
| SCHEMBL7677952 | 0.81 | — | — | |
| SCHEMBL6160443 | 0.81 | PPIA (0.45) | PPIA | |
| SCHEMBL7080456 | 0.80 | — | — | |
| SCHEMBL7688902 | 0.77 | RAB9A (0.40) | CCKBRRAB9A | |
| SCHEMBL6158866 | 0.75 | P2RX7 (0.34) | — | |
| SCHEMBL7086457 | 0.74 | P2RX7 (0.35) | EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1492784-A2 | SUBSTITUTED 2,3-DIPHENYL PYRIDINES | Merck & Co., Inc. (US) | 2005-01-05 | — | — | EP | disclosed |
| WO-2003082191-A2 | SUBSTITUTED 2,3-DIPHENYL PYRIDINES | MERCK & CO., INC. (US) | 2003-10-09 | — | — | WO | disclosed |
| US-6479531-B1 | Gastrin and cholecystokinin receptor ligands | JAMES BLACK FOUNDATION LIMITED (GB) | 2002-11-12 | — | — | US | disclosed |