Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 8/20 | 0.59 |
| ▸ | PPARA | Q07869 | 8/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | PPARD | Q03181 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.49 |
| ▸ | CCKBR | P32239 | 1/20 | 0.49 |
| ▸ | CCR1 | P32246 | 2/20 | 0.48 |
| ▸ | F13A1 | P00488 | 1/20 | 0.47 |
| ▸ | TGM2 | P21980 | 1/20 | 0.47 |
| ▸ | TGM1 | P22735 | 1/20 | 0.47 |
| ▸ | HRH2 | P25021 | 1/20 | 0.47 |
| ▸ | HRH1 | P35367 | 1/20 | 0.47 |
| ▸ | TLR2 | O60603 | 1/20 | 0.46 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6161114 | 1.00 | PPARG (0.59) | PPARGPPARAKMT2APPARDMAPK1 | |
| SCHEMBL6164942 | 0.91 | PPARG (0.48) | PPARGPPARAKMT2APPARDMAPK1 | |
| SCHEMBL6164945 | 0.91 | PPARG (0.48) | PPARGPPARAKMT2APPARDMAPK1 | |
| SCHEMBL2374766 | 0.88 | KMT2A (0.68) | KMT2AMAPK1PABPC1CCR1F13A1 | |
| SCHEMBL2374758 | 0.88 | KMT2A (0.68) | KMT2AMAPK1PABPC1CCR1F13A1 | |
| SCHEMBL6162558 | 0.85 | CCKBR (0.49) | CCKBRCCR1 | |
| SCHEMBL6162563 | 0.85 | CCKBR (0.49) | CCKBRCCR1 | |
| Hydrochloric Acid SCHEMBL6161340 | 0.84 | CCKBR (0.49) | CCKBRCCR1 | |
| Hydrochloric Acid SCHEMBL6161333 | 0.84 | CCKBR (0.49) | CCKBRCCR1 | |
| SCHEMBL21983140 | 0.83 | F13A1 (0.47) | CCKBRCCR1F13A1TGM2TGM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0828754-B1 | DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE | PFIZER (US) | 2005-02-02 | — | — | EP | disclosed |
| US-5936089-A | PIPERIDINE DERIVATIVES; BONE DISORDERS; OBESITY; AGING; CACHEXIA ASSOCIATED WITH AIDS AND CANCER | PFIZER INC (US) | 1999-08-10 | — | — | US | disclosed |