SCHEMBL6162558

SCHEMBL6162558

CC(C)(N)C(=O)N[C@@H](CSCc1ccccc1)C(=O)N1CCC(c2ccccc2)CC1

nearest known ligand 0.49

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CCKBR P32239 1/20 0.49
CCR1 P32246 13/20 0.48
HPN P05981 1/20 0.44
HGFAC Q04756 1/20 0.44
ST14 Q9Y5Y6 1/20 0.44
CHRM4 P08173 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6162563 1.00 CCKBR (0.49) CCKBRCCR1HPNHGFACST14
Hydrochloric Acid SCHEMBL6161340 0.99 CCKBR (0.49) CCKBRCCR1HPNHGFACST14
Hydrochloric Acid SCHEMBL6161333 0.99 CCKBR (0.49) CCKBRCCR1HPNHGFACST14
SCHEMBL6160841 0.86 CCR1 (0.53) CCKBRCCR1
SCHEMBL6160614 0.86 CCR1 (0.53) CCKBRCCR1
SCHEMBL6161114 0.85 PPARG (0.59) CCKBRCCR1
SCHEMBL6161108 0.85 PPARG (0.59) CCKBRCCR1
SCHEMBL6164942 0.84 PPARG (0.48) CCKBRCCR1
SCHEMBL6164945 0.84 PPARG (0.48) CCKBRCCR1
SCHEMBL6166113 0.84 CCR1 (0.52) CCKBRCCR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0828754-B1 DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE PFIZER (US) 2005-02-02 EP claimed