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SCHEMBL6161139

SCHEMBL6161139

CC(C)(C)OC(=O)NC(C)(C)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)N1CCC(Cc2ccccc2)CC1

nearest known ligand 0.66

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 1/20 0.57
▸ KMT2A Q03164 1/20 0.57
▸ BCHE P06276 1/20 0.55
▸ CTSL P07711 2/20 0.52
▸ CTSS P25774 1/20 0.52
▸ CTSK P43235 1/20 0.52
▸ BRS3 P32247 1/20 0.52
▸ CCKAR P32238 1/20 0.51
▸ CCKBR P32239 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6161131 1.00 MEN1 (0.57) MEN1KMT2ABCHECTSLCTSS
SCHEMBL6161560 0.88 MEN1 (0.57) MEN1KMT2ACTSLCTSSCTSK
SCHEMBL6161758 0.87 MEN1 (0.57) MEN1KMT2ACTSLCTSSCTSK
SCHEMBL6164109 0.87 MEN1 (0.57) MEN1KMT2ACTSLCTSSCTSK
SCHEMBL6164270 0.87 BCHE (0.60) MEN1KMT2ABCHEBRS3
SCHEMBL6164274 0.87 BCHE (0.60) MEN1KMT2ABCHEBRS3
Hydrochloric Acid SCHEMBL6164450 0.86 BCHE (0.59) MEN1KMT2ABCHEBRS3
Hydrochloric Acid SCHEMBL6164457 0.86 BCHE (0.59) MEN1KMT2ABCHEBRS3
SCHEMBL6161880 0.85 MEN1 (0.55) MEN1KMT2ACTSLCTSSCTSK
SCHEMBL6161878 0.85 MEN1 (0.55) MEN1KMT2ACTSLCTSSCTSK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0828754-B1 DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE PFIZER (US) 2005-02-02 — — EP disclosed