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Sugi Predict / Compounds / SCHEMBL6161560

SCHEMBL6161560

SCHEMBL6161560

CC(C)(C)OC(=O)NC(C)(C)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)N1CCC(Nc2ccccc2)CC1

nearest known ligand 0.66

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 1/20 0.57
▸ KMT2A Q03164 1/20 0.57
▸ CTSL P07711 2/20 0.50
▸ CTSS P25774 1/20 0.50
▸ CTSK P43235 1/20 0.50
▸ FPR2 P25090 1/20 0.49
▸ PKM P14618 1/20 0.49
▸ TACR1 P25103 2/20 0.48
▸ ACE P12821 1/20 0.47
▸ CCKAR P32238 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6161139 0.88 MEN1 (0.57) MEN1KMT2ACTSLCTSSCTSK
SCHEMBL6161131 0.88 MEN1 (0.57) MEN1KMT2ACTSLCTSSCTSK
SCHEMBL6164109 0.87 MEN1 (0.57) MEN1KMT2ACTSLCTSSCTSK
SCHEMBL6161758 0.87 MEN1 (0.57) MEN1KMT2ACTSLCTSSCTSK
SCHEMBL6161841 0.87 GHSR (0.54) MEN1KMT2AFPR2PKMACE
SCHEMBL6162005 0.87 GHSR (0.54) MEN1KMT2AFPR2PKMACE
Hydrochloric Acid SCHEMBL6168140 0.86 GHSR (0.53) MEN1KMT2AFPR2PKMACE
Hydrochloric Acid SCHEMBL6168134 0.86 GHSR (0.53) MEN1KMT2AFPR2PKMACE
SCHEMBL6161878 0.85 MEN1 (0.55) MEN1KMT2ACTSLCTSSCTSK
SCHEMBL6161880 0.85 MEN1 (0.55) MEN1KMT2ACTSLCTSSCTSK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0828754-B1 DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE PFIZER (US) 2005-02-02 — — EP disclosed