Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 3/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8927888 | 0.78 | MAPT (0.52) | ACHEMAOAMAPTTDP1L3MBTL1 | |
| SCHEMBL23677719 | 0.77 | MEN1 (0.37) | CTSLCTSSCTSKMAPTTDP1 | |
| SCHEMBL14832986 | 0.74 | CTSL (0.45) | CTSLCTSSCTSKMAPTTDP1 | |
| SCHEMBL5716618 | 0.73 | CTSL (0.44) | CTSLCTSSCTSKALDH1A1TRPV3 | |
| SCHEMBL28984736 | 0.73 | CYP1A2 (0.39) | ACHEMAOAMAPTTDP1L3MBTL1 | |
| SCHEMBL4328219 | 0.72 | CTSL (0.46) | CTSLCTSSCTSKTRPV3 | |
| SCHEMBL7995306 | 0.72 | ALDH1A1 (0.41) | RAB9ASMN1; SMN2POLBKDM4EALDH1A1 | |
| Phenol SCHEMBL27620144 | 0.72 | ALDH1A1 (0.41) | MAPTTDP1L3MBTL1RAB9ASMN1; SMN2 | |
| SCHEMBL1547937 | 0.70 | MAPT (0.39) | ACHEMAPTTDP1L3MBTL1RAB9A | |
| SCHEMBL7710900 | 0.69 | CTSL (0.45) | CTSLCTSSCTSKMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0755923-B1 | Ameliorant or remedy for symptoms caused by Ischemic diseases and Phenylpiperidine compounds useful therefor | DAIICHI SUNTORY PHARMA CO LTD (JP) | 2005-05-04 | — | — | EP | disclosed |
| US-6469010-B1 | COMPOSITION ALSO FOR ALLEVIATION OR TREATMENT OF SYMPTOMS DERIVED FROM SEIZURES, EPILEPSY AND MIGRAINE HEADACHES, AND SUPPRESSION OF CALCIUM ION OVERLOAD | SUNTORY LIMITED (JP) | 2002-10-22 | — | — | US | disclosed |