Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 6/20 | 0.63 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.63 |
| ▸ | MPO | P05164 | 6/20 | 0.58 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.48 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.45 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.45 |
| ▸ | SPR | P35270 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6159000 | 0.97 | OPRL1 (0.62) | OPRL1OPRM1MPOSLC6A4MTNR1A | |
| SCHEMBL6163570 | 0.97 | OPRL1 (0.61) | OPRL1OPRM1MPOSLC6A4MTNR1A | |
| Hydrochloric Acid SCHEMBL5339275 | 0.89 | OPRL1 (0.60) | OPRL1OPRM1MTNR1AMEN1KMT2A | |
| SCHEMBL4851081 | 0.87 | OPRL1 (0.69) | OPRL1OPRM1MPOMTNR1AMTNR1B | |
| SCHEMBL6168849 | 0.87 | OPRL1 (0.59) | OPRL1OPRM1MTNR1AMEN1KMT2A | |
| SCHEMBL6160062 | 0.87 | OPRL1 (0.49) | OPRL1OPRM1SLC6A4MTNR1AMTNR1B | |
| SCHEMBL6165082 | 0.86 | OPRL1 (0.58) | OPRL1OPRM1MTNR1AMEN1KMT2A | |
| Citric Acid SCHEMBL4849030 | 0.81 | OPRL1 (0.60) | OPRL1OPRM1MTNR1AMTNR1BNOTUM | |
| SCHEMBL4850795 | 0.80 | OPRL1 (0.76) | OPRL1OPRM1MPOMTNR1AMTNR1B | |
| Hydrochloric Acid SCHEMBL4858864 | 0.79 | OPRL1 (0.76) | OPRL1OPRM1MPOMTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1562891-A1 | 4-AMINOMETHYL-1-ARYL-CYCLOHEXYLAMINE DERIVATIVES | Grünenthal GmbH (DE) | 2005-08-17 | — | — | EP | disclosed |
| WO-2004043899-A1 | 4-AMINOMETHYL-1-ARYL-CYCLOHEXYLAMINE DERIVATIVES | Grünenthal GmbH (DE) | 2004-05-27 | — | — | WO | disclosed |