Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.46 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.46 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.46 |
| ▸ | TACR1 | P25103 | 1/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | JUN | P05412 | 1/20 | 0.37 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.37 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL6161392 | 0.81 | DPP4 (0.48) | DPP4DPP8DPP9TACR1OPRD1 | |
| SCHEMBL2536963 | 0.81 | DPP4 (0.49) | DPP4DPP8DPP9TACR1OPRD1 | |
| SCHEMBL2536966 | 0.81 | DPP4 (0.49) | DPP4DPP8DPP9TACR1OPRD1 | |
| SCHEMBL3743962 | 0.81 | DPP4 (0.49) | DPP4DPP8DPP9TACR1OPRD1 | |
| SCHEMBL7011991 | 0.80 | OPRD1 (0.51) | DPP4DPP8DPP9TACR1OPRD1 | |
| Hydrochloric Acid SCHEMBL3743959 | 0.80 | DPP4 (0.48) | DPP4DPP8DPP9TACR1OPRD1 | |
| SCHEMBL4902378 | 0.80 | OPRD1 (0.51) | DPP4DPP8DPP9TACR1OPRD1 | |
| Hydrochloric Acid SCHEMBL3743965 | 0.80 | DPP4 (0.48) | DPP4DPP8DPP9TACR1OPRD1 | |
| Hydrochloric Acid SCHEMBL7008761 | 0.79 | OPRD1 (0.50) | DPP4DPP8DPP9TACR1OPRD1 | |
| Hydrochloric Acid SCHEMBL4902375 | 0.79 | OPRD1 (0.50) | DPP4DPP8DPP9TACR1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0828754-B1 | DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE | PFIZER (US) | 2005-02-02 | — | — | EP | disclosed |
| US-5936089-A | PIPERIDINE DERIVATIVES; BONE DISORDERS; OBESITY; AGING; CACHEXIA ASSOCIATED WITH AIDS AND CANCER | PFIZER INC (US) | 1999-08-10 | — | — | US | disclosed |
| WO-1996035713-A1 | DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE | PFIZER, INC. (US) | 1996-11-14 | — | — | WO | disclosed |