Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA1 | Q09470 | 4/20 | 0.47 |
| ▸ | KCNAB1 | Q14722 | 4/20 | 0.47 |
| ▸ | DPP4 | P27487 | 1/20 | 0.46 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.46 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.46 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.44 |
| ▸ | F2 | P00734 | 2/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PLG | P00747 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6160849 | 0.99 | DPP8 (0.47) | KCNA1KCNAB1DPP4DPP8DPP9 | |
| Hydrochloric Acid SCHEMBL6169194 | 0.80 | F2 (0.43) | KCNA1KCNAB1F2PLGF10 | |
| SCHEMBL4771020 | 0.79 | HDAC8 (0.68) | KCNA1KCNAB1HDAC8HDAC1ALDH1A1 | |
| SCHEMBL4902572 | 0.79 | HDAC8 (0.68) | KCNA1KCNAB1HDAC8HDAC1ALDH1A1 | |
| SCHEMBL6161443 | 0.79 | P2RX7 (0.47) | F2ALDH1A1F10 | |
| SCHEMBL5556801 | 0.78 | HDAC8 (0.70) | DPP4DPP8DPP9DPP7HDAC8 | |
| SCHEMBL27463800 | 0.78 | F2 (0.41) | KCNA1KCNAB1F2DRD2HTR2A | |
| SCHEMBL6161455 | 0.74 | CHEK2 (0.44) | HDAC8F2DRD2HTR2AHTR2C | |
| SCHEMBL4796773 | 0.72 | HDAC8 (0.65) | HDAC8HDAC1ALDH1A1LMNA | |
| SCHEMBL4796767 | 0.72 | HDAC8 (0.65) | HDAC8HDAC1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0828754-B1 | DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE | PFIZER (US) | 2005-02-02 | — | — | EP | disclosed |