Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK2 | O96017 | 1/20 | 0.44 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.44 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 3/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 3/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6161457 | 0.74 | KCNA1 (0.47) | F2LMNASMN1; SMN2ALDH1A1HTR6 | |
| Hydrochloric Acid SCHEMBL6160849 | 0.73 | DPP8 (0.47) | F2LMNASMN1; SMN2ALDH1A1HTR6 | |
| SCHEMBL24490308 | 0.70 | HTR6 (0.50) | LMNASMN1; SMN2ALDH1A1GAAHTR6 | |
| SCHEMBL9959550 | 0.66 | NLRP3 (0.50) | TMPRSS2LMNASMN1; SMN2ALDH1A1GAA | |
| SCHEMBL3081178 | 0.64 | MEN1 (0.65) | ALDH1A1HTR6HDAC3HDAC4HDAC1 | |
| SCHEMBL5452240 | 0.64 | TMPRSS6 (0.73) | CHEK2SMN1; SMN2ALDH1A1POLB | |
| SCHEMBL3153735 | 0.64 | ESR2 (0.53) | TMPRSS2LMNASMN1; SMN2ALDH1A1GAA | |
| SCHEMBL19329406 | 0.64 | ALDH1A1 (0.75) | LMNASMN1; SMN2ALDH1A1GAAHDAC3 | |
| SCHEMBL29135073 | 0.63 | AR (0.57) | CHEK2LMNASMN1; SMN2ALDH1A1GAA | |
| SCHEMBL3563084 | 0.63 | SLC16A3 (0.75) | GPR27LMNASMN1; SMN2ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0828754-B1 | DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE | PFIZER (US) | 2005-02-02 | — | — | EP | claimed |
| EP-0828754-B1 | DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE | PFIZER (US) | 2005-02-02 | — | — | EP | disclosed |