Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 5/20 | 0.80 |
| ▸ | MAPT | P10636 | 3/20 | 0.80 |
| ▸ | PKM | P14618 | 1/20 | 0.80 |
| ▸ | RAB9A | P51151 | 1/20 | 0.80 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | HTT | P42858 | 2/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | BCHE | P06276 | 3/20 | 0.55 |
| ▸ | ACHE | P22303 | 3/20 | 0.55 |
| ▸ | FAAH | O00519 | 1/20 | 0.55 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | BACE1 | P56817 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8884292 | 0.91 | MAPK1 (0.77) | MAPK1MAPTPKMRAB9ANPSR1 | |
| SCHEMBL6585695 | 0.88 | MAPK1 (0.78) | MAPK1MAPTPKMRAB9ANPSR1 | |
| SCHEMBL3288703 | 0.88 | MAPK1 (0.78) | MAPK1MAPTPKMRAB9ANPSR1 | |
| SCHEMBL6159635 | 0.87 | MAPK1 (1.00) | MAPK1MAPTPKMRAB9ANPSR1 | |
| Hydrochloric Acid SCHEMBL11102389 | 0.86 | MAPK1 (0.97) | MAPK1MAPTPKMRAB9ANPSR1 | |
| SCHEMBL3604839 | 0.85 | MAPK1 (0.74) | MAPK1MAPTPKMRAB9ANPSR1 | |
| SCHEMBL6819927 | 0.82 | MAPK1 (0.80) | MAPK1MAPTPKMRAB9ANPSR1 | |
| SCHEMBL2728614 | 0.81 | HCAR3 (0.64) | MAPK1MAPTPKMRAB9ANPSR1 | |
| SCHEMBL22495122 | 0.81 | HCAR3 (0.59) | MAPK1MAPTPKMRAB9ANPSR1 | |
| SCHEMBL4069632 | 0.81 | MEN1 (0.76) | MAPK1MAPTPKMRAB9ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0828754-B1 | DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE | PFIZER (US) | 2005-02-02 | — | — | EP | disclosed |
| US-5936089-A | PIPERIDINE DERIVATIVES; BONE DISORDERS; OBESITY; AGING; CACHEXIA ASSOCIATED WITH AIDS AND CANCER | PFIZER INC (US) | 1999-08-10 | — | — | US | disclosed |
| CN-1143647-A | Dipeptides which promote release of growth hormone | PFIZER (US) | 1997-02-26 | — | — | CN | disclosed |