SCHEMBL6161692

SCHEMBL6161692

CC(C)(N)C(=O)N[C@H](COCc1ccccc1)C(=O)N1CCC(c2ccccc2)CC1

nearest known ligand 0.58

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
GHSR Q92847 9/20 0.58
CCKBR P32239 2/20 0.49
CCR1 P32246 3/20 0.48
F13A1 P00488 1/20 0.47
TGM2 P21980 1/20 0.47
TGM1 P22735 1/20 0.47
TACR1 P25103 1/20 0.47
CTSL P07711 1/20 0.46
CTSS P25774 1/20 0.46
CTSK P43235 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6161700 1.00 GHSR (0.58) GHSRCCKBRCCR1F13A1TGM2
Hydrochloric Acid SCHEMBL6160707 0.99 GHSR (0.57) GHSRCCKBRCCR1F13A1TGM2
Hydrochloric Acid SCHEMBL6160711 0.99 GHSR (0.57) GHSRCCKBRCCR1F13A1TGM2
SCHEMBL6162935 0.85 PPARA (0.48) GHSRCCKBRCCR1F13A1TGM2
SCHEMBL6162932 0.85 PPARA (0.48) GHSRCCKBRCCR1F13A1TGM2
SCHEMBL6160841 0.85 CCR1 (0.53) CCKBRCCR1F13A1TGM2TGM1
SCHEMBL6160614 0.85 CCR1 (0.53) CCKBRCCR1F13A1TGM2TGM1
SCHEMBL2021273 0.84 GHSR (0.60) GHSRTACR1
SCHEMBL2021271 0.84 GHSR (0.60) GHSRTACR1
SCHEMBL6162514 0.83 GHSR (0.54) GHSRCCKBR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0828754-B1 DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE PFIZER (US) 2005-02-02 EP claimed