Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 13/20 | 0.53 |
| ▸ | F13A1 | P00488 | 1/20 | 0.47 |
| ▸ | TGM2 | P21980 | 1/20 | 0.47 |
| ▸ | TGM1 | P22735 | 1/20 | 0.47 |
| ▸ | CCKBR | P32239 | 1/20 | 0.47 |
| ▸ | CCR10 | P46092 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6160614 | 1.00 | CCR1 (0.53) | CCR1F13A1TGM2TGM1CCKBR | |
| SCHEMBL6166107 | 0.94 | CCR1 (0.52) | CCR1F13A1TGM2TGM1CCKBR | |
| SCHEMBL6166113 | 0.94 | CCR1 (0.52) | CCR1F13A1TGM2TGM1CCKBR | |
| Hydrochloric Acid SCHEMBL6161310 | 0.93 | CCR1 (0.51) | CCR1F13A1TGM2TGM1CCKBR | |
| Hydrochloric Acid SCHEMBL6161307 | 0.93 | CCR1 (0.51) | CCR1F13A1TGM2TGM1CCKBR | |
| SCHEMBL6162563 | 0.86 | CCKBR (0.49) | CCR1CCKBR | |
| SCHEMBL6162558 | 0.86 | CCKBR (0.49) | CCR1CCKBR | |
| Hydrochloric Acid SCHEMBL6161333 | 0.85 | CCKBR (0.49) | CCR1CCKBR | |
| SCHEMBL6161692 | 0.85 | GHSR (0.58) | CCR1F13A1TGM2TGM1CCKBR | |
| SCHEMBL6161700 | 0.85 | GHSR (0.58) | CCR1F13A1TGM2TGM1CCKBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0828754-B1 | DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE | PFIZER (US) | 2005-02-02 | — | — | EP | claimed |
| EP-0828754-A1 | DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE | PFIZER INC. (US) | 1998-03-18 | — | — | EP | claimed |
| WO-1996038471-A1 | DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE | PFIZER INC. (US) | 1996-12-05 | — | — | WO | claimed |
| EP-0828754-B1 | DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE | PFIZER (US) | 2005-02-02 | — | — | EP | disclosed |
| US-5936089-A | PIPERIDINE DERIVATIVES; BONE DISORDERS; OBESITY; AGING; CACHEXIA ASSOCIATED WITH AIDS AND CANCER | PFIZER INC (US) | 1999-08-10 | — | — | US | disclosed |
| EP-0828754-A1 | DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE | PFIZER INC. (US) | 1998-03-18 | — | — | EP | disclosed |
| WO-1996038471-A1 | DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE | PFIZER INC. (US) | 1996-12-05 | — | — | WO | disclosed |