SCHEMBL6161735

SCHEMBL6161735

CC(C)(C)C(=O)N=C=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11232592 0.78
SCHEMBL1485005 0.78
SCHEMBL5453433 0.74
SCHEMBL30430215 0.74
SCHEMBL15228415 0.74 RIPK1 (0.33)
SCHEMBL11659825 0.71
SCHEMBL11659169 0.71
SCHEMBL974183 0.71
SCHEMBL27274500 0.71
SCHEMBL30122284 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12319640-B2 Cyclic diones as herbicidal compounds SYNGENTA CROP PROTECTION AG (CH) 2025-06-03 US disclosed
CN-114222733-B Cyclic diketones as herbicidal compounds 先正达农作物保护股份公司 2025-03-21 CN disclosed
CN-112823150-B Herbicidal 2-azaspiro [3-5] nonane compounds 先正达农作物保护股份公司 2024-09-03 CN disclosed
CN-114080384-B Herbicidal cyclohexanedione derivatives 先正达农作物保护股份公司 2024-07-12 CN disclosed
CN-111886229-B Herbicidal compounds 先正达参股股份有限公司 2023-12-29 CN disclosed
CN-111868034-B Spirocyclic cyclohexanedione derivatives as herbicides 先正达参股股份有限公司 2023-12-01 CN disclosed
US-20220281804-A1 CYCLIC DIONES AS HERBICIDAL COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2022-09-08 US disclosed
EP-4003956-A1 CYCLIC DIONES AS HERBICIDAL COMPOUNDS Syngenta Crop Protection AG (CH) 2022-06-01 EP disclosed
CN-114222733-A Cyclic diones as herbicidal compounds 先正达农作物保护股份公司 2022-03-22 CN disclosed
CN-114080384-A Herbicidal cyclohexanedione derivatives 先正达农作物保护股份公司 2022-02-22 CN disclosed
CN-111868034-A Spirocyclic cyclohexanedione derivatives as herbicides 先正达参股股份有限公司 2020-10-30 CN disclosed
US-20160340361-A1 PIPERIDINE INHIBITORS OF JANUS KINASE 3 AUSPEX PHARMACEUTICALS, INC. 2016-11-24 US disclosed
EP-0893442-B1 LYMPH-ABSORBABLE IMIDAZOLE DERIVATIVES SHIONOGI & CO (JP) 2005-01-12 EP disclosed
US-6054591-A LYMPHOTROPIC ANTI-AIDS AGENT SHIONOGI & CO., LTD. (JP) 2000-04-25 US disclosed
EP-0893442-A1 LYMPH-ABSORBABLE IMIDAZOLE DERIVATIVES SHIONOGI & CO., LTD. (JP) 1999-01-27 EP disclosed
US-5386057-A Process for the preparation of acyl isocyanates SOCIETE NATIONALE DES POUDRES ET EXPLOSIFS (FR) 1995-01-31 US disclosed
EP-0208510-B1 1-SUBSTITUTED OXINDOLE-3-CARBOXAMINES AS ANTIINFLAMMATORY AND ANALGESIC AGENTS PFIZER INC. (US) 1991-09-11 EP disclosed
US-4678802-A ANTIARTHRITIC PFIZER INC. (US) 1987-07-07 US disclosed
EP-0208510-A2 1-Substituted oxindole-3-carboxamines as antiinflammatory and analgesic agents PFIZER INC. (US) 1987-01-14 EP disclosed
CN-86105309-A Oxindole-3-carbonyl amines the compound that replaces as the 1-of anti-inflammatory and anodyne 1987-01-14 CN disclosed