⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6161735 | 0.74 | — | — | |
| SCHEMBL3822372 | 0.72 | — | — | |
| SCHEMBL1605245 | 0.72 | — | — | |
| SCHEMBL26622265 | 0.67 | DGAT1 (0.33) | — | |
| SCHEMBL483875 | 0.65 | — | — | |
| SCHEMBL5690874 | 0.65 | ALDH1A1 (0.33) | — | |
| SCHEMBL30530530 | 0.65 | — | — | |
| SCHEMBL13105332 | 0.65 | — | — | |
| SCHEMBL1513006 | 0.63 | — | — | |
| SCHEMBL15359943 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1309576-B1 | DI(HET)ARYLAMINOTHIAZOLE DERIVATIVES AND THEIR USE IN ORGANIC LIGHT-EMITTING DIODES (OLED'S) AND ORGANIC PHOTOVOLTAIC COMPONENTS | OSRAM OLED GMBH (DE) | 2017-11-22 | — | — | EP | claimed |
| US-20040028943-A1 | Di(het)arylaminothiazole derivatives and their use in organic light-emitting diodes(oleds) and organic photovoltaic components | OSRAM OLED GMBH (DE) | 2004-02-12 | — | — | US | claimed |
| US-20180162862-A1 | INHIBITORS OF BACTERIAL GLYCOSYL TRANSFERASES | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2018-06-14 | — | — | US | disclosed |
| EP-1309576-B1 | DI(HET)ARYLAMINOTHIAZOLE DERIVATIVES AND THEIR USE IN ORGANIC LIGHT-EMITTING DIODES (OLED'S) AND ORGANIC PHOTOVOLTAIC COMPONENTS | OSRAM OLED GMBH (DE) | 2017-11-22 | — | — | EP | disclosed |
| WO-2016191658-A1 | INHIBITORS OF BACTERIAL GLYCOSYL TRANSFERASES | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2016-12-01 | — | — | WO | disclosed |
| US-8420679-B2 | Aminothiazole derivatives and their use as CRF receptor ligands | SANOFI (FR) | 2013-04-16 | — | — | US | disclosed |
| US-7357989-B2 | Di(het)arylaminothiazole derivatives and their use in organic light-emitting diodes(OLEDs) and organic photovoltaic components | OSRAM OPTO SEMICONDUCTORS GMBH (DE) | 2008-04-15 | — | — | US | disclosed |
| US-7357989-B2 | Di(het)arylaminothiazole derivatives and their use in organic light-emitting diodes(OLEDs) and organic photovoltaic components | OSRAM OPTO SEMICONDUCTORS GMBH (DE) | 2008-04-15 | — | — | US | disclosed |
| US-20070281919-A1 | Aminothiazole Derivatives And Their Use As CRF Receptor Ligands | SANOFI-AVENTIS (FR) | 2007-12-06 | — | — | US | disclosed |
| US-7135466-B2 | Quinoline and quinazoline derivatives and drugs containing the same | KIRIN BEER KABUSHIKI KAISHA (JP) | 2006-11-14 | — | — | US | disclosed |
| US-20060211717-A1 | Quinoline and quinazoline derivatives and drugs containing the same | KIRIN BEER KABUSHIKI KAISHA (JP) | 2006-09-21 | — | — | US | disclosed |
| CN-1188476-A | 4-phenylaminothiazole derivatives, method for preparing same, and pharmaceutical compositions thereof | SANOFI SA (FR) | 1998-07-22 | — | — | CN | disclosed |
| CN-1035552-C | branched alkylamino derivatives of thiazoles, process for their preparation and pharmaceutical compositions containing them | SANOFI ELF (FR) | 1997-08-06 | — | — | CN | disclosed |
| US-5602132-A | USEFUL IN TREATMENT OF PATHOLOGIES INVOLVING CORTICOTROPIN RELEASING FACTOR | SANOFI (FR) | 1997-02-11 | — | — | US | disclosed |
| US-5464847-A | Moduators of corticotropin releasing factor | ELF SANOFI (FR) | 1995-11-07 | — | — | US | disclosed |
| US-5378706-A | Memory disorders, senile dememtia | SANOFI (FR) | 1995-01-03 | — | — | US | disclosed |
| CN-1085898-A | branched alkylamino derivatives of thiazoles, process for their preparation and pharmaceutical compositions containing them | SANOFI ELF (FR) | 1994-04-27 | — | — | CN | disclosed |
| US-5232921-A | Thiazole derivatives active on the cholinergic system, process for obtention and pharmaceutical compositions | SANOFI (FR) | 1993-08-03 | — | — | US | disclosed |
| EP-0283390-B1 | THIAZOLE DERIVATIVES ACTIVE ON THE CHOLINERGIC SYSTEM, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ELF SANOFI (FR) | 1993-03-03 | — | — | EP | disclosed |
| EP-0283390-A2 | Thiazole derivatives active on the cholinergic system, process for their preparation and pharmaceutical compositions containing them | ELF SANOFI (FR) | 1988-09-21 | — | — | EP | disclosed |