SCHEMBL6161842

SCHEMBL6161842

CCCCCCCCCCCCOC(=O)C(C)OC(=O)c1ccc(Cl)c(N)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.49
NPC1 O15118 2/20 0.49
RAB9A P51151 2/20 0.49
MAPT P10636 1/20 0.49
KDM4E B2RXH2 4/20 0.44
HSD17B10 Q99714 2/20 0.44
POLB P06746 1/20 0.44
CASP3 P42574 1/20 0.42
SENP8 Q96LD8 1/20 0.42
SENP7 Q9BQF6 1/20 0.42
SENP6 Q9GZR1 1/20 0.42
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
HPGD P15428 3/20 0.42
LMNA P02545 2/20 0.42
CYP1A2 P05177 1/20 0.42
CYP3A4 P08684 1/20 0.42
CYP2C9 P11712 1/20 0.42
TSHR P16473 1/20 0.42
CYP2C19 P33261 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11116165 0.86 ALDH1A1 (0.65) ALDH1A1NPC1RAB9AMAPTKDM4E
SCHEMBL10416281 0.86 ALDH1A1 (0.65) ALDH1A1NPC1RAB9AMAPTKDM4E
SCHEMBL8897849 0.86 ALDH1A1 (0.65) ALDH1A1NPC1RAB9AMAPTKDM4E
SCHEMBL2892370 0.86 ALDH1A1 (0.65) ALDH1A1NPC1RAB9AMAPTKDM4E
SCHEMBL6161836 0.86 ALDH1A1 (0.43) ALDH1A1NPC1RAB9AMAPTLMNA
SCHEMBL11481988 0.83 ALDH1A1 (0.41) ALDH1A1NPC1RAB9AMAPTLMNA
SCHEMBL11481987 0.83 ALDH1A1 (0.41) ALDH1A1NPC1RAB9AMAPTLMNA
SCHEMBL13607645 0.83 ALDH1A1 (0.72) ALDH1A1NPC1RAB9AMAPTKDM4E
SCHEMBL9459003 0.83 ALDH1A1 (0.49) ALDH1A1NPC1RAB9AMAPTLMNA
SCHEMBL10913700 0.82 ALDH1A1 (0.44) ALDH1A1NPC1RAB9AMAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0711758-B1 Method of manufacturing a 3-substituted-3-oxo-2-halopropionic acid amide compound and method of manufacturing a 3-substituted-3-oxo-2-(5,5-dimethylhydantoin-3-yl) propionic acid amide compound FUJI PHOTO FILM CO LTD (JP) 2005-01-26 EP disclosed
EP-0853077-B1 Process for producing alkyl 3-amino-4-substituted benzoates SANKIO CHEMICAL CO LTD (JP) 2003-04-16 EP disclosed
EP-1020450-A1 Method of manufacturing a 3-substituted-3-oxo-2-halopropionic acid amide compound and method of manufacturing a 3-substituted-3-oxo-2-(5,5-dimethylhydantoin-3-yl) propionic acid amide compound FUJI PHOTO FILM CO., LTD. (JP) 2000-07-19 EP disclosed
US-5908955-A 3-AMINO-4-SUBSTITUTED BENZOIC ACID OR AN ALKALI METAL SALT THEREOF IS ALLOWED TO REACT WITH AN ALKYL HALIDE IN THE PRESENCE OF A BASIC CARBONATE SANKIO CHEMICAL CO., LTD. (JP) 1999-06-01 US disclosed
EP-0853077-A1 Process for producing alkyl 3-amino-4-substituted benzoates Sankio Chemical Co., Ltd. (JP) 1998-07-15 EP disclosed
US-5672714-A HALOGENATION WITH 1,3-DIHALO-5,5-DIMETHYLHYDANTOIN FOLLOWED BY REACTION WITH 5,5-DIMETHYLHYDANTOIN AT THE HALOGENATION SITE TO FORM PHOTOGRAPHIC YELLOW COUPLER COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1997-09-30 US disclosed
EP-0711758-A2 Method of manufacturing a 3-substituted-3-oxo-2-halopropionic acid amide compound and method of manufacturing a 3-substituted-3-oxo-2-(5,5-dimethylhydantoin-3-yl) propionic acid amide compound FUJI PHOTO FILM CO., LTD. (JP) 1996-05-15 EP disclosed
US-4476219-A GALLIC AMIDE DERIVATIVE, HIGH SPEED REACTION COUPLER FUJI PHOTO FILM CO., LTD. (JP) 1984-10-09 US disclosed
US-4474874-A PREVENTS FORMATION OF COLOR FOG, TRIHYDROXY BENZENE COMPOUND FUJI PHOTO FILM COMPANY LIMITED (JP) 1984-10-02 US disclosed
US-4200466-A Light-sensitive silver halide photographic materials KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1980-04-29 US disclosed