Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 6/20 | 0.41 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.40 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | STS | P08842 | 5/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8897841 | 0.86 | ALDH1A1 (0.57) | ALDH1A1NPC1MAPTRAB9AESR1 | |
| SCHEMBL2450252 | 0.86 | ALDH1A1 (0.57) | ALDH1A1NPC1MAPTRAB9AESR1 | |
| SCHEMBL6161842 | 0.86 | ALDH1A1 (0.49) | ALDH1A1NPC1MAPTRAB9ATSHR | |
| SCHEMBL11481988 | 0.85 | ALDH1A1 (0.41) | ALDH1A1NPC1MAPTRAB9AESR1 | |
| SCHEMBL11481987 | 0.83 | ALDH1A1 (0.41) | ALDH1A1NPC1MAPTRAB9AESR1 | |
| SCHEMBL9459003 | 0.83 | ALDH1A1 (0.49) | ALDH1A1NPC1MAPTRAB9AESR1 | |
| SCHEMBL11035872 | 0.82 | ALDH1A1 (0.54) | ALDH1A1NPC1MAPTRAB9AESR1 | |
| SCHEMBL8930406 | 0.81 | MAPT (0.43) | ALDH1A1NPC1MAPTRAB9AESR1 | |
| SCHEMBL8930408 | 0.81 | MAPT (0.43) | ALDH1A1NPC1MAPTRAB9AESR1 | |
| SCHEMBL13607645 | 0.78 | ALDH1A1 (0.72) | ALDH1A1NPC1MAPTRAB9AESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711758-B1 | Method of manufacturing a 3-substituted-3-oxo-2-halopropionic acid amide compound and method of manufacturing a 3-substituted-3-oxo-2-(5,5-dimethylhydantoin-3-yl) propionic acid amide compound | FUJI PHOTO FILM CO LTD (JP) | 2005-01-26 | — | — | EP | disclosed |
| EP-1020450-A1 | Method of manufacturing a 3-substituted-3-oxo-2-halopropionic acid amide compound and method of manufacturing a 3-substituted-3-oxo-2-(5,5-dimethylhydantoin-3-yl) propionic acid amide compound | FUJI PHOTO FILM CO., LTD. (JP) | 2000-07-19 | — | — | EP | disclosed |
| US-5672714-A | HALOGENATION WITH 1,3-DIHALO-5,5-DIMETHYLHYDANTOIN FOLLOWED BY REACTION WITH 5,5-DIMETHYLHYDANTOIN AT THE HALOGENATION SITE TO FORM PHOTOGRAPHIC YELLOW COUPLER COMPOUND | FUJI PHOTO FILM CO., LTD. (JP) | 1997-09-30 | — | — | US | disclosed |
| EP-0711758-A2 | Method of manufacturing a 3-substituted-3-oxo-2-halopropionic acid amide compound and method of manufacturing a 3-substituted-3-oxo-2-(5,5-dimethylhydantoin-3-yl) propionic acid amide compound | FUJI PHOTO FILM CO., LTD. (JP) | 1996-05-15 | — | — | EP | disclosed |