Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.30 |
| ▸ | TOP2A | P11388 | 1/20 | 0.30 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6161001 | 0.89 | ENPP2 (0.35) | KDM4EALDH1A1HSD17B10ENPP2HTT | |
| SCHEMBL6161983 | 0.87 | ENPP2 (0.32) | ENPP2 | |
| SCHEMBL6167205 | 0.85 | ENPP2 (0.34) | KDM4EALDH1A1ENPP2HTT | |
| SCHEMBL6965855 | 0.84 | ENPP2 (0.33) | ENPP2 | |
| SCHEMBL6961504 | 0.83 | ENPP2 (0.35) | KDM4EALDH1A1ENPP2HTTTOP2A | |
| SCHEMBL6160633 | 0.82 | PPARG (0.33) | ALDH1A1ENPP2 | |
| SCHEMBL6159794 | 0.82 | PPARG (0.33) | ALDH1A1ENPP2 | |
| SCHEMBL6161870 | 0.82 | PPARG (0.33) | ALDH1A1ENPP2 | |
| SCHEMBL597334 | 0.81 | P2RX3 (0.33) | KDM4EALDH1A1ENPP2MAPTHTT | |
| SCHEMBL5623522 | 0.81 | ENPP2 (0.32) | KDM4EALDH1A1ENPP2HTTS1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0893442-B1 | LYMPH-ABSORBABLE IMIDAZOLE DERIVATIVES | SHIONOGI & CO (JP) | 2005-01-12 | — | — | EP | disclosed |