SCHEMBL6161942

SCHEMBL6161942

CC(C)(N)C(=O)N[C@H](Cc1cccc2ccccc12)C(=O)N1CCC(c2ccccc2)CC1

nearest known ligand 0.50

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.47
CALCRL Q16602 1/20 0.47
CCR1 P32246 6/20 0.46
HPN P05981 2/20 0.44
HGFAC Q04756 2/20 0.44
ST14 Q9Y5Y6 2/20 0.44
GHSR Q92847 3/20 0.42
SIGMAR1 Q99720 1/20 0.42
CCKBR P32239 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL6162218 0.99 CYP3A4 (0.46) CYP3A4CALCRLCCR1HPNHGFAC
Hydrochloric Acid SCHEMBL6162214 0.99 CYP3A4 (0.46) CYP3A4CALCRLCCR1HPNHGFAC
SCHEMBL6162570 0.86 CYP3A4 (0.47) CYP3A4CALCRLGHSRCCKBR
Hydrochloric Acid SCHEMBL6161020 0.85 CYP3A4 (0.46) CYP3A4CALCRLGHSRCCKBR
Hydrochloric Acid SCHEMBL6161026 0.85 CYP3A4 (0.46) CYP3A4CALCRLGHSRCCKBR
SCHEMBL6161500 0.85 CALCRL (0.49) CYP3A4CALCRLCCR1
SCHEMBL6161491 0.85 CALCRL (0.49) CYP3A4CALCRLCCR1
SCHEMBL6162859 0.85 CTSS (0.49) CYP3A4CALCRLCCR1HPNHGFAC
SCHEMBL6162850 0.85 CTSS (0.49) CYP3A4CALCRLCCR1HPNHGFAC
Hydrochloric Acid SCHEMBL6161544 0.84 CALCRL (0.49) CYP3A4CALCRLCCR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0828754-B1 DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE PFIZER (US) 2005-02-02 EP claimed