Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.47 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | GHSR | Q92847 | 4/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | MME | P08473 | 1/20 | 0.40 |
| ▸ | ACE | P12821 | 1/20 | 0.40 |
| ▸ | CPA1 | P15085 | 1/20 | 0.40 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.40 |
| ▸ | MC4R | P32245 | 1/20 | 0.40 |
| ▸ | CCKBR | P32239 | 1/20 | 0.40 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6161020 | 0.99 | CYP3A4 (0.46) | CYP3A4CALCRLCTSSCTSKLMNA | |
| Hydrochloric Acid SCHEMBL6161026 | 0.99 | CYP3A4 (0.46) | CYP3A4CALCRLCTSSCTSKLMNA | |
| SCHEMBL6161942 | 0.86 | CYP3A4 (0.47) | CYP3A4CALCRLGHSRCCKBR | |
| SCHEMBL6162213 | 0.86 | GHSR (0.54) | CALCRLGHSRACE | |
| SCHEMBL6162222 | 0.86 | GHSR (0.54) | CALCRLGHSRACE | |
| Hydrochloric Acid SCHEMBL6162218 | 0.85 | CYP3A4 (0.46) | CYP3A4CALCRLGHSRMC4RCCKBR | |
| Hydrochloric Acid SCHEMBL6162214 | 0.85 | CYP3A4 (0.46) | CYP3A4CALCRLGHSRMC4RCCKBR | |
| Hydrochloric Acid SCHEMBL6159893 | 0.85 | GHSR (0.53) | CALCRLGHSRACE | |
| Hydrochloric Acid SCHEMBL6159888 | 0.85 | GHSR (0.53) | CALCRLGHSRACE | |
| SCHEMBL6164327 | 0.79 | CALCRL (0.75) | CYP3A4CALCRL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0828754-B1 | DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE | PFIZER (US) | 2005-02-02 | — | — | EP | disclosed |
| US-5936089-A | PIPERIDINE DERIVATIVES; BONE DISORDERS; OBESITY; AGING; CACHEXIA ASSOCIATED WITH AIDS AND CANCER | PFIZER INC (US) | 1999-08-10 | — | — | US | disclosed |