Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 8/20 | 0.59 |
| ▸ | PPARA | Q07869 | 8/20 | 0.59 |
| ▸ | LTA4H | P09960 | 4/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.55 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.54 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | HTR5A | P47898 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11837347 | 0.85 | PPARG (0.58) | PPARGPPARALTA4HSIGMAR1S1PR1 | |
| Hydrochloric Acid SCHEMBL11838153 | 0.84 | PPARG (0.57) | PPARGPPARALTA4HSIGMAR1S1PR1 | |
| Hydrochloric Acid SCHEMBL11839971 | 0.83 | PPARG (0.56) | PPARGPPARALTA4HSIGMAR1S1PR1 | |
| SCHEMBL11839619 | 0.81 | PPARG (0.56) | PPARGPPARALTA4HSIGMAR1S1PR1 | |
| SCHEMBL7729504 | 0.78 | SIGMAR1 (0.64) | SIGMAR1MEN1KMT2A | |
| SCHEMBL7729507 | 0.78 | CYP2D6 (0.52) | PPARGPPARASIGMAR1MEN1KMT2A | |
| SCHEMBL11835059 | 0.78 | PPARG (0.61) | PPARGPPARASIGMAR1S1PR1S1PR3 | |
| SCHEMBL8725506 | 0.78 | LTA4H (0.56) | PPARGPPARALTA4HSIGMAR1S1PR1 | |
| Hydrochloric Acid SCHEMBL11843021 | 0.77 | PPARG (0.60) | PPARGPPARASIGMAR1S1PR1S1PR3 | |
| Hydrochloric Acid SCHEMBL11832653 | 0.76 | PPARG (0.61) | PPARGPPARASIGMAR1S1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0755923-B1 | Ameliorant or remedy for symptoms caused by Ischemic diseases and Phenylpiperidine compounds useful therefor | DAIICHI SUNTORY PHARMA CO LTD (JP) | 2005-05-04 | — | — | EP | disclosed |
| US-6469010-B1 | COMPOSITION ALSO FOR ALLEVIATION OR TREATMENT OF SYMPTOMS DERIVED FROM SEIZURES, EPILEPSY AND MIGRAINE HEADACHES, AND SUPPRESSION OF CALCIUM ION OVERLOAD | SUNTORY LIMITED (JP) | 2002-10-22 | — | — | US | disclosed |
| US-6048876-A | ANTICONVULSANTS; ANTIEPILEPIC AGENT | SUNTORY LIMITED (JP) | 2000-04-11 | — | — | US | disclosed |
| EP-0755923-A1 | AMELIORANT OR REMEDY FOR SYMPTOMS CAUSED BY ISCHEMIC DISEASES AND COMPOUNDS USEFUL THEREFOR | SUNTORY LIMITED (JP) | 1997-01-29 | — | — | EP | disclosed |