Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALCRL | Q16602 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | ECE1 | P42892 | 1/20 | 0.49 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.48 |
| ▸ | FPR2 | P25090 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | HTR1B | P28222 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | GHSR | Q92847 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6162000 | 1.00 | CALCRL (0.53) | CALCRLMEN1KMT2AECE1P2RY12 | |
| SCHEMBL6163760 | 0.86 | CALCRL (0.54) | CALCRLMEN1KMT2AP2RY12FPR2 | |
| SCHEMBL6163764 | 0.86 | CALCRL (0.54) | CALCRLMEN1KMT2AP2RY12FPR2 | |
| Hydrochloric Acid SCHEMBL6163192 | 0.85 | CALCRL (0.54) | CALCRLMEN1KMT2AP2RY12FPR2 | |
| Hydrochloric Acid SCHEMBL6163197 | 0.85 | CALCRL (0.54) | CALCRLMEN1KMT2AP2RY12FPR2 | |
| SCHEMBL6161281 | 0.85 | P2RY12 (0.52) | CALCRLMEN1KMT2AP2RY12FPR2 | |
| SCHEMBL6161284 | 0.85 | P2RY12 (0.52) | CALCRLMEN1KMT2AP2RY12FPR2 | |
| SCHEMBL6161607 | 0.84 | SMYD3 (0.52) | CALCRLMEN1KMT2AP2RY12FPR2 | |
| Hydrochloric Acid SCHEMBL6161916 | 0.84 | P2RY12 (0.51) | CALCRLMEN1KMT2AP2RY12FPR2 | |
| Hydrochloric Acid SCHEMBL6166180 | 0.84 | CALCRL (0.51) | CALCRLMEN1KMT2AECE1P2RY12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0828754-B1 | DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE | PFIZER (US) | 2005-02-02 | — | — | EP | disclosed |