Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD3 | Q9H7B4 | 4/20 | 0.52 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.49 |
| ▸ | DPP4 | P27487 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MPO | P05164 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | SOS1 | Q07889 | 5/20 | 0.47 |
| ▸ | KRAS | P01116 | 1/20 | 0.47 |
| ▸ | FPR2 | P25090 | 1/20 | 0.46 |
| ▸ | AKT1 | P31749 | 1/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6161918 | 0.99 | SMYD3 (0.51) | SMYD3CALCRLDPP4MEN1KMT2A | |
| SCHEMBL6163764 | 0.85 | CALCRL (0.54) | CALCRLMEN1KMT2AFPR2P2RY12 | |
| SCHEMBL6163760 | 0.85 | CALCRL (0.54) | CALCRLMEN1KMT2AFPR2P2RY12 | |
| Hydrochloric Acid SCHEMBL6163192 | 0.85 | CALCRL (0.54) | CALCRLMEN1KMT2AFPR2P2RY12 | |
| Hydrochloric Acid SCHEMBL6163197 | 0.85 | CALCRL (0.54) | CALCRLMEN1KMT2AFPR2P2RY12 | |
| SCHEMBL6161993 | 0.84 | CALCRL (0.53) | CALCRLMEN1KMT2AFPR2P2RY12 | |
| SCHEMBL6162000 | 0.84 | CALCRL (0.53) | CALCRLMEN1KMT2AFPR2P2RY12 | |
| SCHEMBL6161281 | 0.84 | P2RY12 (0.52) | SMYD3CALCRLMEN1KMT2AFPR2 | |
| SCHEMBL6161284 | 0.84 | P2RY12 (0.52) | SMYD3CALCRLMEN1KMT2AFPR2 | |
| SCHEMBL6163835 | 0.84 | BRD4 (0.54) | SMYD3DPP4LMNAFPR2AKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0828754-B1 | DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE | PFIZER (US) | 2005-02-02 | — | — | EP | claimed |